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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
12/15-lipoxygenase
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "12/15-lipoxygenase" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi .
1
1 Cited Publications
Cat. No.: HY-P72076
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ALOX12; Platelet 12-LOX; Arachidonate 12-lipoxygenase, 12S Type; LOG12; 12S-LOX; Arachidonate 15-lipoxygenase,15S-Type; Polyunsaturated Fatty Acid lipoxygenase ALOX12; Platelet-Type 12-lipoxygenase; Arachidonate 12-lipoxygenase, 12S-Type; Arachidonate 12-lipoxygenase; Arachidonate (12S)-lipoxygenase; Linoleate (13S)-lipoxygenase; Arachidonate (15S)-lipoxygenase; Linoleate 13S-lipoxygenase; Platelet-Type lipoxygenase 12; 12-LOX; Lipoxin Synthase 12-LO; 12LO; 12S-lipoxygenase
Species:
Human
Source:
E. coli
Cat. No.: HY-W010697
CAS No.: 604-33-1
Target:
Synonyms: CDC
Target:
Research Areas:
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent 12/15-Lipoxygenases (LO) inhibitor. Cinnamyl-3,4-dihydroxy-α-cyanocinnamate has the potential for the research of type 1 diabetes mellitus .
Cat. No.: HY-175970
CAS No.: 423735-70-0
Target:
Research Areas:
MLS000099089 is a 12/15-lipoxygenase (12/15-LOX) inhibitor with IC50 values of 3.4 μM and 10 μM for human and mice 12/15-LOX, respectively. MLS000099089 displays higher selectivity for 12/15-LOX over 5-LOX and COX-2. MLS000099089 can be used for the study of stroke .
Cat. No.: HY-W010697S
Cholesteryl linoleate-d11 is the d11-labeled Cholesteryl linoleate (HY-W010697). Cholesteryl linoleate is a cholesteryl ester with antibacterial activity that is present in low-density lipoprotein (LDL) particles, human nasal fluid, and respiratory epithelial secretions. Cholesteryl linoleate is oxidized by 12/15-lipoxygenase in macrophages and participates in selective uptake and efflux via LDL receptor-related protein. Cholesteryl linoleate does not induce endothelial adhesion molecule expression, nor does it induce monocyte binding to endothelial cells. Cholesteryl linoleate liposomal formulations inhibit the growth of multiple bacteria at physiological nasal fluid concentrations and act synergistically with antimicrobial peptides. Cholesteryl linoleate is useful for research related to atherosclerosis and bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
