Search Result
Results for "
5′ phosphates
" in MedChemExpress (MCE) Product Catalog:
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- HY-N2581
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myo-Inositol, hexakisdihydrogen phosphate sodium salt; Inositol hexaphosphate sodium salt
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MOFs
Endogenous Metabolite
Amyloid-β
Autophagy
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
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Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) sodium salt is an orally active compound. Phytic acid sodium salt can be derived from the seeds of legumes. Phytic acid sodium salt is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid sodium salt attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid sodium salt can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research [5] .
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- HY-N0814
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Inositol hexaphosphate; SNF472 free acid
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Endogenous Metabolite
Amyloid-β
Autophagy
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
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Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Phytic acid can be derived from the seeds of legumes. Phytic acid is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research [5] .
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- HY-W011727S
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Pyridoxal 5'-phosphate-d3
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Endogenous Metabolite
Amyloid-β
ERK
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Neurological Disease
Metabolic Disease
Cancer
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Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
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- HY-176533
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LPL Receptor
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Neurological Disease
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S1PR5-IN-1 (Compound 7a) is a highly selective S1PR5 antagonist and orally bioavailable inhibitor with a human S1PR5 IC50 of 85.4 nM and human S1PR5 Kd of 2.173 nM.S1PR5-IN-1 binds to S1PR5 and inhibits natural killer cell migration toward sphingosine-1-phosphate.S1PR5-IN-1 can be used for the research of multiple sclerosis .
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- HY-108496S
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S1P-d7
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Endogenous Metabolite
LPL Receptor
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Endocrinology
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Sphingosine-1-phosphate-d7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12.?Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids .
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- HY-N2580
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Endogenous Metabolite
Amyloid-β
Autophagy
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
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Zinc Phytate (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Zinc Phytate can be derived from the seeds of legumes. Zinc Phytate is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. Zinc Phytate attenuates Aβ oligomers and upregulates autophagy protein. Zinc Phytate can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research [5] .
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- HY-118010A
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d-Norfenfluramine hydrochloride
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5-HT Receptor
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Cardiovascular Disease
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(+)-Norfenfluramine hydrochloride, a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT2B receptor agonist (Ki: 11.2 nM). (+)-Norfenfluramine hydrochloride potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca 2+. (+)-Norfenfluramine hydrochloride can be used for the research of primary pulmonary hypertension and valvular heart disease .
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- HY-W131725
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d-Norfenfluramine
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5-HT Receptor
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Cardiovascular Disease
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(+)-Norfenfluramine a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT2B receptor agonist (Ki: 11.2 nM). (+)-Norfenfluramine potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca 2+. (+)-Norfenfluramine can be used for the research of primary pulmonary hypertension and valvular heart disease .
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- HY-172741
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Drug Derivative
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Metabolic Disease
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Dioctanoyl PI(3,5)P2 sodium is a synthetic analog of PI(3,5)P2 (a natural phosphatidylinositol). Phosphatidylinositol phosphates (PIPs) are intracellular
amphiphilic molecules implicated in numerous cellular responses including growth, division, movement, differentiation, neuro-exocytosis, and survival .
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- HY-P2881
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Nucleoside 5′-diphosphate kinase
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Biochemical Assay Reagents
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Cancer
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Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) belongs to the family of structurally and functionally conserved NDPK (Nucleotide diphosphate kinase) enzymes. Nucleoside diphosphate kinase catalyzes the reversible transfer of γ-phosphates between nucleoside di-(NDP) and triphosphates (NTP) through ping-pong bi-bi reaction kinetics. Nucleoside diphosphate kinase is the essential housekeeping proteins that produces CTP (cytidine triphosphate) for lipid syntheses, UTP (Uridine triphosphate) for polysaccharide syntheses, and GTP (guanosine triphosphate) for protein syntheses, signal transduction, and microtubules polymerization .
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- HY-B1744S
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- HY-160113D
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Biochemical Assay Reagents
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Others
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Sodium phosphate buffer 0.1M, pH 7.5 is mainly composed of two phosphates, Na2HPO4 and NaH2PO4, with a total phosphate concentration of 0.1 M, which mainly acts as a buffer in the reaction.
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- HY-113280S
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- HY-137608
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UDP-β-S
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P2Y Receptor
DNA/RNA Synthesis
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Cardiovascular Disease
Inflammation/Immunology
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Uridine 5'-O-thiodiphosphate (UDP-β-S) is a P2Y6 receptor agonist with an EC50 of 25 nM. Uridine 5'-O-thiodiphosphate resists degradation by extracellular nucleotidases and stimulates the accumulation of inositol phosphates. Uridine 5'-O-thiodiphosphate stimulates contractile responses in endothelium-denuded rat mesenteric arteries. As a mitogen, Uridine 5'-O-thiodiphosphate stimulates DNA synthesis, [ 3H] thymidine incorporation, protein synthesis, [ 3H]leucine incorporation, and increases the number of vascular smooth muscle cells. Uridine 5'-O-thiodiphosphate can be used in the research of cardiovascular diseases such as atherosclerosis .
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- HY-137608A
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UDP-β-S trisodium
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P2Y Receptor
DNA/RNA Synthesis
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Cardiovascular Disease
Inflammation/Immunology
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Uridine 5'-O-thiodiphosphate trisodium (UDP-β-S trisodium) is a P2Y6 receptor agonist with an EC50 of 25 nM. Uridine 5'-O-thiodiphosphate trisodium resists degradation by extracellular nucleotidases and stimulates the accumulation of inositol phosphates. Uridine 5'-O-thiodiphosphate trisodium stimulates contractile responses in endothelium-denuded rat mesenteric arteries. As a mitogen, Uridine 5'-O-thiodiphosphate trisodium stimulates DNA synthesis, [ 3H] thymidine incorporation, protein synthesis, [ 3H]leucine incorporation, and increases the number of vascular smooth muscle cells. Uridine 5'-O-thiodiphosphate trisodium can be used in the research of cardiovascular diseases such as atherosclerosis .
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- HY-120985
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Calcium Channel
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Neurological Disease
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Xestospongins and araguspongins are marine natural products first isolated from Pacific basin sponges, and noted to have vasodilatory properties.1 Inositol phosphates (IP) are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores.2 Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level in cerebral microsomes, with an IC50 of 0.6 μM. It is nearly as potent as xestospongin C as an antagonist of the IP3 receptor.
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- HY-E70382
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Phosphatase
Biochemical Assay Reagents
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Others
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Shrimp Alkaline Phosphatase (SAP), a nucleotide phosphatase, can catalyze the removal of 5′ phosphates from nucleic acid templates. Shrimp Alkaline Phosphatase is readily inactivated in the absence of chelators and is widely used phosphatases in molecular cloning .
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- HY-W721166
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Riboflavine phosphate-d3 sodium; Riboflavin 5'-phosphate-d3 sodium; Riboflavine 5'-phosphate-d3 sodium
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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Riboflavin phosphate-d3 sodium (Riboflavine phosphate-d3 sodium; Riboflavin 5'-phosphate-d3 sodium; Riboflavine 5'-phosphate-d3 sodium) is the deuterium labeled Riboflavin phosphate sodium (HY-B0964). Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium is a very effective NAD+-recycling agent .
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- HY-165664S
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Glyceol 2-Phosphate-d5 sodium salt hydrate
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Isotope-Labeled Compounds
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Others
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β-Glycerophosphate-d5 (Glyceol 2-Phosphate-d5) sodium salt hydrateis deuterium labeled β-Glycerophosphate (sodium salt hydrate) .
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- HY-W392933S5
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Thymidine-5'-phosphate-d13 dilithium
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Isotope-Labeled Compounds
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Others
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Thymidine 5'-monophosphate-d13 (Thymidine-5'-phosphate-d13) dilithium is deuterium labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-13570CS
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Apoptosis
Glucocorticoid Receptor
Isotope-Labeled Compounds
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Others
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Betamethasone 21-phosphate-d5 is the deuterium labeled Betamethasone disodium phosphate. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids .
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- HY-146874S
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Isotope-Labeled Compounds
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Others
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D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]propyl hydrogen phosphate]-d5, ammonium salt (1:1) is an isotopically labeled compound.
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- HY-146873S
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Isotope-Labeled Compounds
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Others
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D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-tetradecen-1-yl]oxy]propyl hydrogen phosphate]-d5, ammonium salt (1:1) is an isotopically labeled compound.
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- HY-W750265
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- HY-P2863A
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Endogenous Metabolite
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Metabolic Disease
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Deoxyribonuclease II, Bovine (EC 3.1.22.1) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA yielding products with 3'-phosphates. In vitro, its optimum pH range is 4.5-5.0. Deoxyribonuclease II, Bovine (EC 3.1.22.1) also acts upon p-nitrophenyl-phosphodiesters at pH 5.6-5.9.
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- HY-182650
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Biochemical Assay Reagents
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Others
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Nitsch Medium (With Sucrose) is composed of potassium salts, calcium chloride, magnesium sulfate, phosphates, etc., with a potassium salt concentration of 2575.5 mg/L, a magnesium sulfate concentration of 246.5 mg/L, and an ammonium salt concentration of 720 mg/L. Nitsch Medium (With Sucrose) has a high vitamin content and is a sterile solution.
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- HY-182650B
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Biochemical Assay Reagents
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Others
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Nitsch Medium (With Sucrose, Agar) is mainly composed of potassium salts, calcium chloride, magnesium sulfate, and phosphates. The potassium salt concentration is 2575.5 mg/L, the magnesium sulfate concentration is 246.5 mg/L, and the ammonium salt concentration is 720 mg/L. Nitsch Medium (With Sucrose, Agar) has a high vitamin content and is a sterile solution.
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- HY-182650C
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Biochemical Assay Reagents
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Others
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Nitsch Medium (Agar-Free, Sucrose-Free) is mainly composed of potassium nitrate, calcium chloride, magnesium sulfate, and phosphates. The concentrations are: potassium nitrate 2575.5 mg/L, magnesium sulfate 246.5 mg/L, and ammonium nitrate 720 mg/L. Nitsch Medium (Agar-Free, Sucrose-Free) has a high vitamin content and is a sterile solution.
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- HY-181448
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Inositol hexaphosphate hexalithium; SNF472 hexalithium
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Endogenous Metabolite
Amyloid-β
Autophagy
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
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Phytic acid (Inositol hexaphosphate hexalithium) hexalithium is an orally active compound. Phytic acid hexalithium can be derived from the seeds of legumes. Phytic acid is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid hexalithium attenuates Aβ oligomers and upregulates Autophagy protein. Phytic acid hexalithium can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research [5] .
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- HY-160113D
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生化学アッセイ試薬
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Sodium phosphate buffer 0.1M, pH 7.5 is mainly composed of two phosphates, Na2HPO4 and NaH2PO4, with a total phosphate concentration of 0.1 M, which mainly acts as a buffer in the reaction.
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- HY-182650
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生化学アッセイ試薬
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Nitsch Medium (With Sucrose) is composed of potassium salts, calcium chloride, magnesium sulfate, phosphates, etc., with a potassium salt concentration of 2575.5 mg/L, a magnesium sulfate concentration of 246.5 mg/L, and an ammonium salt concentration of 720 mg/L. Nitsch Medium (With Sucrose) has a high vitamin content and is a sterile solution.
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- HY-182650B
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生化学アッセイ試薬
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Nitsch Medium (With Sucrose, Agar) is mainly composed of potassium salts, calcium chloride, magnesium sulfate, and phosphates. The potassium salt concentration is 2575.5 mg/L, the magnesium sulfate concentration is 246.5 mg/L, and the ammonium salt concentration is 720 mg/L. Nitsch Medium (With Sucrose, Agar) has a high vitamin content and is a sterile solution.
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- HY-182650C
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生化学アッセイ試薬
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Nitsch Medium (Agar-Free, Sucrose-Free) is mainly composed of potassium nitrate, calcium chloride, magnesium sulfate, and phosphates. The concentrations are: potassium nitrate 2575.5 mg/L, magnesium sulfate 246.5 mg/L, and ammonium nitrate 720 mg/L. Nitsch Medium (Agar-Free, Sucrose-Free) has a high vitamin content and is a sterile solution.
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| 製品番号 |
製品名 |
Category |
Target |
構造式 |
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- HY-W011727S
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Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
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- HY-108496S
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Sphingosine-1-phosphate-d7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12.?Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids .
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- HY-B1744S
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Pyridoxal phosphate-d5 is the deuterium labeled Pyridoxal phosphate. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia .
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- HY-113280S
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Pyridoxol 5'-phosphate-d3 is deuterium labeled Pyridoxine 5'-phosphate.
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- HY-W721166
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Riboflavin phosphate-d3 sodium (Riboflavine phosphate-d3 sodium; Riboflavin 5'-phosphate-d3 sodium; Riboflavine 5'-phosphate-d3 sodium) is the deuterium labeled Riboflavin phosphate sodium (HY-B0964). Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium is a very effective NAD+-recycling agent .
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- HY-165664S
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β-Glycerophosphate-d5 (Glyceol 2-Phosphate-d5) sodium salt hydrateis deuterium labeled β-Glycerophosphate (sodium salt hydrate) .
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- HY-W392933S5
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Thymidine 5'-monophosphate-d13 (Thymidine-5'-phosphate-d13) dilithium is deuterium labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-13570CS
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Betamethasone 21-phosphate-d5 is the deuterium labeled Betamethasone disodium phosphate. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids .
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- HY-146874S
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D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]propyl hydrogen phosphate]-d5, ammonium salt (1:1) is an isotopically labeled compound.
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- HY-146873S
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D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-tetradecen-1-yl]oxy]propyl hydrogen phosphate]-d5, ammonium salt (1:1) is an isotopically labeled compound.
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- HY-W750265
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Dexamethasone Phosphate-d5 is the deuterium labeled Dexamethasone Phosphate-d5 (HY-W750265) .
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