19036-73-8
Chemical Structure
(+)-Norfenfluramine
Synonym(s): d-Norfenfluramine
- CAS. Nr.: 19036-73-8
- Formula:C10H12F3N
- Molecular Weight:203.20
IUPAC Name: (S)-1-(3-(trifluoromethyl)phenyl)propan-2-amine
InChIKey: MLBHFBKZUPLWBD-ZETCQYMHSA-N
SMILES: C=1(C=C(C=CC1)C(F)(F)F)C[C@H](C)N
Biological Activity: (+)-Norfenfluramine a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT2B receptor agonist (Ki: 11.2 nM). (+)-Norfenfluramine potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca2+. (+)-Norfenfluramine can be used for the research of primary pulmonary hypertension and valvular heart disease[1].
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(+)-Norfenfluramine | 98.79% | (+)-Norfenfluramine a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT2B receptor agonist (Ki: 11.2 nM). (+)-Norfenfluramine potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca2+. (+)-Norfenfluramine can be used for the research of primary pulmonary hypertension and valvular heart disease. | ||||||||||||||||||||
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