37936-89-3
Chemical Structure
(+)-Norfenfluramine hydrochloride
Synonym(s): d-Norfenfluramine hydrochloride
- CAS No.: 37936-89-3
- Formula:C10H13ClF3N
- Molecular Weight:239.67
IUPAC Name: (S)-1-(3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride
InChIKey: PIDLOFBRTWNFAR-FJXQXJEOSA-N
SMILES: N[C@@H](C)CC1=CC=CC(C(F)(F)F)=C1.[H]Cl
Biological Activity: (+)-Norfenfluramine hydrochloride, a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT2B receptor agonist (Ki: 11.2 nM). (+)-Norfenfluramine hydrochloride potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca2+. (+)-Norfenfluramine hydrochloride can be used for the research of primary pulmonary hypertension and valvular heart disease[1].
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(+)-Norfenfluramine hydrochloride | 99.77% | (+)-Norfenfluramine hydrochloride, a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT2B receptor agonist (Ki: 11.2 nM). (+)-Norfenfluramine hydrochloride potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca2+. (+)-Norfenfluramine hydrochloride can be used for the research of primary pulmonary hypertension and valvular heart disease. | ||||||||||||||||||||
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