Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
5-Fluorouridine 5'-phosphate
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "5-Fluorouridine 5'-phosphate" in MCE Product Catalog:
Cat. No.: HY-W784565
CAS No.: 796-66-7
Target:
Research Areas:
5-Fluorouridine 5'-phosphate is an ODCase (orotidine-5′-monophosphate decarboxylase) inhibitor, with a Ki value of 98 µM for human ODCase and a Ki value of 645 µM for Methanobacterium ODCase. 5-Fluorouridine 5'-phosphate exhibits inhibitory activity against leukemia and lymphoma cell lines and can be used in cancer research .
17
17 Cited Publications
Synonyms: Potassium azaorotate; Potassium otastat; Oteracil potassium
Target:
Research Areas:
Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
9
Research Areas:
5-Fluorouridine, a metabolite of5-Fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis .
Cat. No.: HY-W009538
CAS No.: 66335-38-4
Synonyms: 5-Fluoro-5'-deoxycytidine
Research Areas:
5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
Cat. No.: HY-107856R
CAS No.: 316-46-1
Research Areas:
5-Fluorouridine (Standard) is the analytical standard of 5-Fluorouridine. This product is intended for research and analytical applications. 5-Fluorouridine, a metabolite of5-Fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis .
Cat. No.: HY-138943
CAS No.: 149965-92-4
Synonyms: 5'-O-β-D-galactosyl-5-Fluorouridine
Target:
Research Areas:
5-Fluorouridine 5'-O-β-D-galactopyranoside (5'-O-β-D-galactosyl-5-fluorouridine) is a 5-Fluorouridine proagent. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be converted by the enzyme β-D-galactosidase to the potent antineoplastic agent 5-Fluorouridine .
Synonyms: 2’-Deoxy-5-Fluorouridine 5’-phosphate triethylammonium
Research Areas:
FdUMP triethylammonium is the intracellular active form of 5-fluorouracil (5-FU). 5-FU is converted to FdUMP after being transported into the cell by various enzymes. FdUMP forms a ternary complex with thymidylate synthase and its cofactor 5,10-methylene tetrahydrofolate, inhibiting the activity of thymidylate synthase, which in turn leads to the suppression of DNA synthesis.
Cat. No.: HY-134178A
Synonyms: 5-Fluorouridine-5'-triphosphate trisodium
Target:
Research Areas:
5-F-UTP (5-Fluorouridine-5'-triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-P5372A
Research Areas:
Cat. No.: HY-152630
CAS No.: 18829-83-9
Target:
Research Areas:
3’-Deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-W009538R
CAS No.: 66335-38-4
Synonyms: 5-Fluoro-5'-deoxycytidine (Standard)
Research Areas:
5'-Deoxy-5-fluorocytidine (Standard) is the analytical standard of 5'-Deoxy-5-fluorocytidine (HY-W009538). This product is intended for research and analytical applications. 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
Target:
Research Areas:
5-F-UTP (5-Fluorouridine-5'-triphosphate) is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-19514
CAS No.: 174638-15-4
Target:
Research Areas:
Fosfluridine Tidoxil is comprised of a specific carrier molecule, coupled through a phosphate group to 5-Fluorouridine (5-FUrd), a metabolite of 5- Fluorouracil (5-FU). Fosfluridine Tidoxil is a oral active anticancer agent .
Cat. No.: HY-134178S1
Synonyms: 5-Fluorouridine 5'-triphosphate-13C,19F,d1
Cat. No.: HY-P5373
CAS No.: 237409-87-9
Target:
Research Areas:
Cat. No.: HY-P5372
CAS No.: 211190-38-4
Research Areas:
Target:
Research Areas:
1-(b-D-Xylofuranosyl)-5-fluorouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-154141
Target:
Research Areas:
3’-Beta-C-Ethynyl-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Beta-C-Ethynyl-5-fluorouridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-154556
CAS No.: 15379-30-3
Target:
Research Areas:
2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-152783
Target:
Research Areas:
5’(R)-C-Methyl-5-fluorouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
