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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
A3G
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "A3G" in MCE Product Catalog:
Cat. No.: HY-158452
Synonyms: A3G3 N-linked oligosaccharide; A3G(4)3 glycan
Cat. No.: HY-120157
CAS No.: 374679-27-3
Vif-ElonginC interaction inhibitor 1 (compound VEC-5) is a potent Vif inhibitor. Vif-ElonginC interaction inhibitor 1 can restrict HIV-1 in Vif-nonpermissive cells. Vif-ElonginC interaction inhibitor 1 can protect A3G, APOBEC3C (A3C), and APOBEC3F (A3F) from Vif-mediated degradation and drastically inhibit Vif function through blocking the interaction between Vif and ElonginC. Vif-ElonginC interaction inhibitor 1 enhances A3G incorporation into HIV-1 virions to reduce viral infectivity .
Cat. No.: HY-158489
Synonyms: A3G3 N-linked oligosaccharide, procainamide labelled; A3G(4)3 glycan, procainamide labelled
Cat. No.: HY-124870
CAS No.: 357441-99-7
N.41 is an antiviral agent. N.41 protects APOBEC3G (an antiviral factor) from HIV Vif protein-mediated degradation. N.41 inhibits the Vif-A3G interaction and increases cellular A3G levels and incorporation of A3G into virions, thereby attenuating virus infectivity in a Vif-dependent manner. N.41 inhibits HIV-1 viral replication in PBMCs (IC50: 8.4 μM) .
Cat. No.: HY-183925
CAS No.: 52962-95-5
Target:
Research Areas:
Redoxal is a dihydroorotate dehydrogenase (DHODH) inhibitor and anti-HIV-1 agent. Redoxal induces intracellular pyrimidine depletion by inhibiting the de novo pyrimidine biosynthesis pathway, enhances the protein stability of APOBEC3G (A3G), upregulates the abundance of A3G protein in cells and progeny viral particles, thereby strengthening the host endogenous antiviral restriction mediated by A3G . Redoxal selectively targets DHOdehase at the mitochondrial level, with an IC50 of 430 nM for inhibiting DHO oxidation in human mitochondria and an IC50 of 910 nM in rat mitochondria . Redoxal can be used in studies related to HIV-1 infection .
Cat. No.: HY-RS00840
Target:
Research Areas:
APOBEC3G Human Pre-designed siRNA Set A contains three designed siRNAs for APOBEC3G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-158488
Synonyms: A3G3 N-linked oligosaccharide, 2-AB labelled
Cat. No.: HY-158537
Synonyms: A3G3S3 N-linked oligosaccharide, procainamide labelled
Cat. No.: HY-158487
Synonyms: A3G3 N-linked oligosaccharide, 2-AA labelled
Cat. No.: HY-158533
Synonyms: A3G3S3 N-linked oligosaccharide, 2-AA labelled
Cat. No.: HY-158535
Synonyms: A3G3S3 N-linked oligosaccharide, 2-AB labelled
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
