1 Result for "

ACE536

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ACE536" in MCE Product Catalog:

5
5 Cited Publications
Art. -Nr.: HY-P99720
CAS. Nr.: 1373715-00-4
Synonyms: ACE-536; luspatercept–aamt

Target:  

TGF-beta/Smad

Forschungsgebiete:  

Cardiovascular Disease

Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .
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