1 Result for "

ACH4471

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ACH4471" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-117930
CAS No.: 1903768-17-1
Purity:  99.91%
Synonyms: ACH-4471
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
loading...
    loading...