1. Immunology/Inflammation
  2. Complement System
  3. Danicopan

Danicopan 

Cat. No.: HY-117930 Purity: 99.91%
Handling Instructions

Danicopan, a selective and orally active small-molecule factor D inhibitor, inhibits alternative pathway of complement (APC) activity. Danicopan has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).

For research use only. We do not sell to patients.

Danicopan Chemical Structure

Danicopan Chemical Structure

CAS No. : 1903768-17-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 511 In-stock
Estimated Time of Arrival: December 31
5 mg USD 400 In-stock
Estimated Time of Arrival: December 31
10 mg USD 700 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2500 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Danicopan, a selective and orally active small-molecule factor D inhibitor, inhibits alternative pathway of complement (APC) activity. Danicopan has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)[1].

IC50 & Target

Factor D[1]

Molecular Weight

580.41

Formula

C₂₆H₂₃BrFN₇O₃

CAS No.

1903768-17-1

SMILES

O=C([[email protected]]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)C[[email protected]](F)C1)NC5=NC(Br)=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Danicopan
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HY-117930
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