4 Results for "

ACT 128800

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "ACT 128800" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-10569
CAS No.: 854107-55-4
Purity:  99.78%
Synonyms: ACT-128800
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation .
loading...
    loading...
Cat. No.: HY-10569R
CAS No.: 854107-55-4
Synonyms: ACT-128800 (Standard)
Research Areas:  

Inflammation/Immunology

Ponesimod (Standard) is the analytical standard of Ponesimod. This product is intended for research and analytical applications. Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation .
loading...
    loading...
Cat. No.: HY-10569S
Synonyms: ACT-128800-d4
Ponesimod-d4 (ACT-128800-d4) is the deuterium labeled Ponesimod (HY-10569) . Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation .
loading...
    loading...
Cat. No.: HY-10569S1
Purity:  96.50%
Synonyms: ACT-128800-d7
Ponesimod-d7 (ACT-128800-d7) is the deuterium-labeled Ponesimod (HY-10569). Ponesimod-d7 (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod-d7 activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod-d7 can protect against lymphocyte-mediated tissue inflammation .
loading...
    loading...