1 Result for "

ACZ885

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ACZ885" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-108810
CAS No.: 914613-48-2
Purity:  99.64%
Synonyms: Ilaris; ACZ 885
Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin .
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