914613-48-2
914613-48-2
Chemical Structure
Canakinumab
Synonym(s): Ilaris; ACZ 885
- CAS No.: 914613-48-2
- Formula:N/A
- Molecular Weight:(145.5 kDa)
SMILES: [Canakinumab]
Biological Activity: Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2].
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Canakinumab | 98.84% | Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin. | ||||||||||||||||||||
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