1 Result for "

ADC 1013

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ADC 1013" in MCE Product Catalog:

1
1 Cited Publications
製品番号: HY-P99742
CAS 番号: 2055640-86-1
別名: ADC-1013; JNJ-64457107; Vanalimab

Target:  

TNF Receptor

研究分野:  

Cancer

Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment .
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