1 Result for "

AES350

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AES350" in MCE Product Catalog:

Cat. No.: HY-138831
CAS No.: 847249-57-4
Purity:  99.30%
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 μM and 0.245 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research .
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