1 Result for "

AP736

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AP736" in MCE Product Catalog:

Cat. No.: HY-157010
CAS No.: 1365531-21-0
Target:  

Tyrosinase PKA

Research Areas:  

Others

AP736 is a potent tyrosinase inhibitor (IC50 = 0.9 μM) with anti-melanogenesis activity in normal human melanocytes (IC50 = 0.11 μM). AP736 suppresses the expression of tyrosinase and TRP-1/2 by inhibiting the cAMP-PKA-CREB signalling axis, leading to reduced microphthalmia-associated transcription factor (MITF) transcripts and proteins. AP736 can be used for melanogenesis and hyperpigmentation research .
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