3 Results for "

ASP2453

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "ASP2453" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P0227
CAS No.: 168482-23-3
Target:  

Melanocortin Receptor

Research Areas:  

Metabolic Disease

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.
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2
2 Cited Publications
Cat. No.: HY-132966
CAS No.: 2241719-73-1
Purity:  98.28%
Target:  

Ras ERK

Research Areas:  

Cancer

ASP2453 is a potent, selective and orally active KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
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Cat. No.: HY-P1208
CAS No.: 667430-81-1
Target:  

Melanocortin Receptor

Research Areas:  

Inflammation/Immunology

PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo .
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