5 Results for "

AST2818

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "AST2818" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-112870
CAS No.: 1869057-83-9
Purity:  99.89%
Synonyms: Alflutinib; Furmonertinib; AST2818
Target:  

EGFR

Research Areas:  

Cancer

Firmonertinib (Alflutinib; Furmonertinib) is an orally active, mutant-selective, and highly brain penetrant EGFR inhibitor. Firmonertinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation .
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6
6 Cited Publications
Cat. No.: HY-112870A
CAS No.: 2130958-55-1
Purity:  99.97%
Synonyms: Alflutinib mesylate; Furmonertinib mesylate; AST2818 mesylate
Target:  

EGFR

Research Areas:  

Inflammation/Immunology Cancer

Firmonertinib (Alflutinib; Furmonertinib) mesylate is is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. Firmonertinib mesylate inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib mesylate has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation .
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Cat. No.: HY-138627A
CAS No.: 2929417-90-1
Purity:  98.75%
Target:  

EGFR Drug Metabolite

Research Areas:  

Cancer

AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor .
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Cat. No.: HY-138627AR
CAS No.: 2929417-90-1
Research Areas:  

Cancer

AST5902 (trimesylate) (Standard) is the analytical standard of AST5902 (trimesylate). This product is intended for research and analytical applications. AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor[1].
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Cat. No.: HY-112870AS
Synonyms: Alflutinib-d3 mesylate; Furmonertinib-d3 mesylate; AST2818-d3 mesylate
Firmonertinib-d3 (Alflutinib-d3) mesylate is the deuterium labeled Firmonertinib mesylate (HY-112870A). Firmonertinib (Alflutinib; Furmonertinib) mesylate is is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. Firmonertinib mesylate inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib mesylate has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.
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