1 Result for "

AVX754

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "AVX754" in MCE Product Catalog:

Cat. No.: HY-14913
CAS No.: 160707-69-7
Synonyms: SPD754; AVX754
Apricitabine (SPD754; AVX754), the (-) enantiomer of 2′-deoxy-3′-oxa-4′-thiocytidine (dOTC), is a highly selective and orally active HIV-1 reverse transcriptase (RT) inhibitor (Ki=0.08 μM), as well as inhibits DNA polymerases α, β, and γ with Ki value of 300 μM, 12 μM, and 112.25 μM, respectively . Apricitabine (SPD754; AVX754) shows promising antiretroviral efficacy, good tolerability and a low propensity for resistance selection in antiretroviral-naive HIV infection .
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