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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
AY2
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "AY2" in MCE Product Catalog:
Cat. No.: HY-174871
Research Areas:
AY-2 is a binding ligand for FTH1 and can be used to synthesize PROTACs such as AY-4 (HY-174867) .
Cat. No.: HY-174867
CAS No.: 3091513-13-9
Target:
Research Areas:
AY-4 (Compound AY-4) is an efficient PROTAC degrader targeting FTH1 (Kd = 3.17 nM). AY-4 effectively upregulates the levels of ferrous (Fe 2+) and ferric (Fe 3+) ions in cells. AY-4 is a potential anticancer candidate compound that regulates iron homeostasis through ferritin degradation and enhances the efficacy of existing drugs. AY-4 can effectively reduce the level of FTH1 in breast cancer cells (Pink: FTH1 ligand AY-2 (HY-174871); Blue: E3 ligand Pomalidomide (HY-10984); Black: Linker, Pomalidomide-PEG3-acid (HY-174872)) .
Cat. No.: HY-P705090
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike; S protein; Spike glycoprotein; S glycoprotein; AY.1/AY.2/AY.3; Delta Plus
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
