6 Results for "

Afatinib (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Afatinib (Standard)" in MCE Product Catalog:

Cat. No.: HY-10261R
CAS No.: 850140-72-6
Synonyms: BIBW 2992 (Standard)
Afatinib (Standard) is the analytical standard of Afatinib. This product is intended for research and analytical applications. Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer .
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Cat. No.: HY-10261BR
CAS No.: 439081-18-2
Synonyms: (E/Z)-BIBW 2992 (Standard)
(E/Z)-Afatinib (Standard) is the analytical standard of (E/Z)-Afatinib. This product is intended for research and analytical applications. (E/Z)-Afatinib ((E/Z)-BIBW 2992) is the mixture of (E)-Afatinib and (Z)-Afatinib. Afatinib (HY-10261) is an irreversible inhibitor of EGFR, by irreversibly binding to their ATP binding site to block activation of EGFR, HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide (HY-17364), potently targeting to EGFRvIII-cMet signaling in glioblastoma cells .
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Cat. No.: HY-10261AR
CAS No.: 850140-73-7
Synonyms: BIBW 2992MA2 (Standard)
Afatinib (dimaleate) (Standard) is the analytical standard of Afatinib (dimaleate). This product is intended for research and analytical applications. Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer .
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Cat. No.: HY-Z2286R
CAS No.: 1092365-58-6
Target:  

Reference Standards

(2Z)-4-(Dimethylamino)-2-butenoic Acid (Afatinib Impurity) (Standard) is the analytical standard of (2Z)-4-(Dimethylamino)-2-butenoic Acid (Afatinib Impurity). This product is intended for research and analytical applications.
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Cat. No.: HY-Z3727R
CAS No.: 50913-12-7
Target:  

Reference Standards

N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-D-ornithine (Afatinib Impurity) (Standard) is the analytical standard of N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-D-ornithine (Afatinib Impurity). This product is intended for research and analytical applications.
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Cat. No.: HY-Z3995R
CAS No.: 74874-10-5
Target:  

Reference Standards

(2R,4R)-1-[(2S)-5-[[Imino(nitroamino)methyl]amino]-2- [[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid (Afatinib Impurity) (Standard) is the analytical standard of (2R,4R)-1-[(2S)-5-[[Imino(nitroamino)methyl]amino]-2- [[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid (Afatinib Impurity). This product is intended for research and analytical applications.
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