282 Results for "

Angiotensin-converting Enzyme (ACE)

" in MedChemExpress (MCE) Product Catalog:
Products (282)

282 Results for "Angiotensin-converting Enzyme (ACE)" in MCE Product Catalog:

42
42 Publications Verification
Cat. No.: HY-14393
CAS No.: 518-82-1
Purity:  99.25%
Synonyms: Frangula emodin
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
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23
23 Cited Publications
Cat. No.: HY-B0368
CAS No.: 62571-86-2
Synonyms: SQ 14225
Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM .
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14
14 Cited Publications
Cat. No.: HY-12404
CAS No.: 908-54-3
Purity:  99.16%
Synonyms: Diminazene diaceturate
Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties .
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8
8 Cited Publications
Cat. No.: HY-N2165
CAS No.: 23666-13-9
Vicenin 2, a flavonoid, is an orally active angiotensin-converting enzyme (ACE) inhibitor (IC50 of 43.83 μM) . Vicenin 2 has radioprotective, anti-nociceptive effects, anti-glycation anti-inflammatory, antioxidant, anticancer, antiangiogenic properties .
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3
3 Cited Publications
Cat. No.: HY-B0477
CAS No.: 82586-55-8
Synonyms: CI-906
Quinapril (hydrochloride) (CI-906) is a proagent that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.
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3
3 Cited Publications
Cat. No.: HY-B0382
CAS No.: 88889-14-9
Synonyms: SQ28555
Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
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3
3 Cited Publications
Cat. No.: HY-B0231A
CAS No.: 76420-72-9
Synonyms: MK-422 anhydrous
Enalaprilat (MK-422 anhydrous), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat can be used for the research of hypertension .
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3
3 Cited Publications
Cat. No.: HY-B0231
CAS No.: 84680-54-6
Synonyms: MK-422
Enalaprilat dihydrate (MK-422), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat dihydrate can be used for the research of hypertension .
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3
3 Cited Publications
Cat. No.: HY-106446
CAS No.: 80830-42-8
Purity:  99.59%
Synonyms: SA-446
Rentiapril is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity .
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3
3 Cited Publications
Cat. No.: HY-B0093
CAS No.: 86541-75-5
Synonyms: CGS14824A free base
Benazepril (CGS14824A free base) is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. Benazepril improves diabetic nephropathy and decreases proteinuria. Benazepril can be used in the study of hypertension, heart failure and diabetic nephropathy .
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3
3 Cited Publications
Cat. No.: HY-B0093A
CAS No.: 86541-74-4
Synonyms: CGS14824A
Benazepril (CGS14824A) hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril hydrochloride inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. In addition, Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria. Benazepril hydrochloride can be used in the study of hypertension, heart failure and diabetic nephropathy .
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3
3 Cited Publications
Cat. No.: HY-N0214
CAS No.: 19773-24-1
Synonyms: Ebeiensine
Peimisine (Ebeiensine) is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .
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3
3 Cited Publications
Cat. No.: HY-N0214A
CAS No.: 900498-44-4
Synonyms: Ebeiensine hydrochloride
Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .
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3
3 Cited Publications
Cat. No.: HY-W010991
CAS No.: 64967-39-1
Synonyms: FAPGG
Research Areas:  

Others

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546×10 -4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system .
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2
2 Cited Publications
Cat. No.: HY-B0279
CAS No.: 87333-19-5
Synonyms: HOE-498
Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
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2
2 Cited Publications
Cat. No.: HY-B0384
CAS No.: 110221-44-8
Temocapril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor. Temocapril hydrochloride can be used for the research of hypertension, congestive heart failure, acute myocardial infarction, insulin resistance, and renal diseases .
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2
2 Cited Publications
Cat. No.: HY-100713
CAS No.: 111902-57-9
Purity:  98.14%
Temocapril is an orally active angiotensin-converting enzyme (ACE) inhibitor. Temocapril can be used for the research of hypertension, congestive heart failure, acute myocardial infarction, insulin resistance, and renal diseases .
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2
2 Cited Publications
Cat. No.: HY-122445
CAS No.: 41307-63-5
Purity:  99.87%
Resorcinolnaphthalein is a specific angiotensin-converting enzyme 2 (ACE2) enhancer and activates ACE2 activity with an EC50 value of 19.5 μM. Resorcinolnaphthalein can be used for the investigation of hypertension and renal fibrosis .
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2
2 Cited Publications
Cat. No.: HY-P7441
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I converting Enzyme 2; Angiotensin converting Enzyme 2; Angiotensin-converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I converting Enzyme (Peptidyl-Dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-converting Enzy
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2
2 Cited Publications
Cat. No.: HY-P7992
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACE; Angiotensin I converting Enzyme (Peptidyl-Dipeptidase A) 1; Prev. DCP1; DCP; Angiotensin-converting Enzyme; Dipeptidyl Carboxypeptidase 1; Dipeptidyl Carboxypeptidase I; Angiotensin converting Enzyme; Kininase II; Peptidyl-Dipeptidase A; CD143; Carbo
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