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Results for "

Anti-infective

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amyloid-β (2) Antibiotic (28) Autophagy (3) Bacterial (50) Biochemical Assay Reagents (3) Carbonic Anhydrase (1) CCR (3) COX (8) Dihydrofolate reductase (DHFR) (1) DNA Methyltransferase (2) Drug Intermediate (1) Drug Metabolite (1) Elastase (1) Endogenous Metabolite (1) Environmental Pollutants (2) ERK (1) Fungal (7) GSK-3 (1) HCV (1) Herbicide (1) HIV (6) IKK (2) Influenza Virus (13) Integrin (1) Interleukin Related (1) Isotope-Labeled Compounds (4) JNK (1) Keap1-Nrf2 (2) NF-κB (2) p38 MAPK (2) Parasite (17) Prostaglandin Receptor (1) Proteasome (2) Reactive Oxygen Species (ROS) (2) Reference Standards (11) TNF Receptor (1) TRP Channel (5) Virus Protease (3)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Endocrinology (5) Infection (77) Inflammation/Immunology (24) Neurological Disease (5)

By Targets:

Akt (1)

Amyloid-β (2)

Antibiotic (28)

Autophagy (3)

Bacterial (50)

Biochemical Assay Reagents (3)

Carbonic Anhydrase (1)

CCR (3)

COX (8)

Dihydrofolate reductase (DHFR) (1)

DNA Methyltransferase (2)

Drug Intermediate (1)

Drug Metabolite (1)

Elastase (1)

Endogenous Metabolite (1)

Environmental Pollutants (2)

ERK (1)

Fungal (7)

GSK-3 (1)

HCV (1)

Herbicide (1)

HIV (6)

IKK (2)

Influenza Virus (13)

Integrin (1)

Interleukin Related (1)

Isotope-Labeled Compounds (4)

JNK (1)

Keap1-Nrf2 (2)

NF-κB (2)

p38 MAPK (2)

Parasite (17)

Prostaglandin Receptor (1)

Proteasome (2)

Reactive Oxygen Species (ROS) (2)

Reference Standards (11)

TNF Receptor (1)

TRP Channel (5)

Virus Protease (3)

By Research Areas:

Cancer (24)

Cardiovascular Disease (1)

Endocrinology (5)

Infection (77)

Inflammation/Immunology (24)

Neurological Disease (5)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14397

Indomethacin Maximum Cited Publications 76 Publications Verification Indometacin	COX Antibiotic Influenza Virus Bacterial	Inflammation/Immunology Cancer
Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

HY-B2230

Hinokitiol Maximum Cited Publications 8 Publications Verification β-Thujaplicin	Keap1-Nrf2 DNA Methyltransferase Virus Protease	Infection Cancer
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

HY-14882

Cenicriviroc 5+ Cited Publications TAK-652; TBR-652	CCR HIV	Infection Endocrinology
Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity .

HY-121636

Resolvin D2 5 Publications Verification RvD2	TRP Channel	Infection Neurological Disease Inflammation/Immunology
Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC₅₀ = 0.1 nM) and TRPA1 (IC₅₀ = 2 nM) in primary sensory neurons .

HY-N0808

Camphor 3 Publications Verification (±)-Camphor	Environmental Pollutants TRP Channel Influenza Virus	Infection Inflammation/Immunology Cancer
Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-B1350

Fusidic acid 2 Publications Verification Fusidate; SQ-16603	Bacterial Antibiotic	Infection Cancer
Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome. Fusidic acid holds promise for research in anticancer and anti-infective applications. .

HY-12687

Tizoxanide 10+ Cited Publications TIZ	Bacterial HIV Autophagy Parasite IKK Influenza Virus	Infection Cancer
Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide *anti-infective* compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has *anti-HIV-1* activities and potent inhibition of both HBV and HCV replication with values EC₅₀ of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .

HY-14882A

Cenicriviroc Mesylate 5+ Cited Publications TAK-652 Mesylate; TBR-652 Mesylate	CCR HIV	Infection Inflammation/Immunology Endocrinology
Cenicriviroc Mesylate (TAK-652 Mesylate) is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity.

HY-19892A

Brilacidin tetrahydrochloride 1 Publications Verification PMX 30063 tetrahydrochloride	Bacterial Antibiotic	Infection Cancer
Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin tetrahydrochloride is a defensin mimetic antibiotic compound .

HY-B1864A

Kasugamycin hydrochloride 1 Publications Verification Ksg hydrochloride	Environmental Pollutants Antibiotic Bacterial	Infection
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .

HY-14397A

Indomethacin sodium hydrate Maximum Cited Publications 76 Publications Verification Indometacin sodium hydrate	COX Bacterial Influenza Virus Antibiotic	Infection Neurological Disease Inflammation/Immunology Cancer
Indomethacin (Indometacin) sodium hydrateis a orally active and BBB-permeable COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research .

HY-N0677A

Kalii Dehydrographolidi Succinas 1 Publications Verification Potassium dehydroandrographolide succinate	Antibiotic	Infection Inflammation/Immunology
Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate) is an antibiotic. Kalii Dehydrographolidi Succinas exerts immunostimulatory, anti-infective and anti-inflammatory effects . Kalii Dehydrographolidi Succinas shows potential for research on viral pneumonia and viral upper respiratory tract infections .

HY-B1864B

Kasugamycin hydrochloride hydrate 1 Publications Verification Ksg hydrochloride hydrate	Antibiotic Bacterial	Infection
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .

HY-N0677

Dehydroandrographolide succinate 1 Publications Verification	Influenza Virus Prostaglandin Receptor Akt GSK-3	Infection Inflammation/Immunology Cancer
Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED₅₀ = 386.9 mg/kg) by decreasing TXB₂ levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways .

HY-B0914A

10-Undecenoic acid zinc salt 2 Publications Verification Zinc undecylenate	Fungal Bacterial Amyloid-β Reactive Oxygen Species (ROS) Proteasome	Infection Neurological Disease Endocrinology Cancer
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-16349

Nimorazole 1 Publications Verification K-1900	Parasite Antibiotic	Infection Cancer
Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .

HY-B1437

Acetarsol Stovarsol; Acetarsone	Parasite	Infection
Acetarsol (Stovarsol) is a potent and orally active anti-infective agent. Acetarsol shows anti-parasite activity. Acetarsol has the potential for the research of proctitis .

HY-W290527

2-Isopropyl-5-methylanisole	Antibiotic Bacterial	Infection
2-Isopropyl-5-methylanisole is an inhibitor of Mycobacterium tuberculosis chorismate mutase (CM) with an IC₅₀ of 21.58 μM. The MIC of 2-Isopropyl-5-methylanisole for Mycobacterium tuberculosis is 152.22 µM. 2-Isopropyl-5-methylanisole holds potential for research in the field of anti-infective studies .

HY-14737A

Ceftaroline fosamil hydrate 2 Publications Verification TAK-599 hydrate; PPI0903 hydrate	Antibiotic Bacterial	Infection
Ceftaroline fosamil hydrate is a potent cephalosporin antibiotic. Ceftaroline fosamil hydrateshows broad-spectrum activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, and common Gram-negative organisms. Ceftaroline fosamil hydrate has anti-infective activity, and can be used for the research of complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP) .

HY-151485

Anti-infective agent 5	Parasite	Infection
Anti-infective agent 5 (compound 74) is an orally active inhibitor of *Trypanosoma cruzi* with an IC₅₀ value of 0.10 μM. Anti-infective agent 5 effectively reduces parasite burden in vivo. Anti-infective agent 5 can be used for the research of infection .

HY-P5812

IDR 1002	Integrin	Inflammation/Immunology
IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of β1-integrin, a mechanism that promotes monocyte recruitment .

HY-N0808R

Camphor (Standard) (±)-Camphor (Standard)	Reference Standards TRP Channel Influenza Virus	Infection Inflammation/Immunology Cancer
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-14397R

Indomethacin (Standard) Indometacin (Standard)	Reference Standards COX Antibiotic Influenza Virus Bacterial	Inflammation/Immunology Cancer
Indomethacin (Standard) is the analytical standard of Indomethacin. This product is intended for research and analytical applications. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

HY-W069721

N-Acetylsulfanilamide 4-Acetamidobenzenesulfonamide	Carbonic Anhydrase Drug Metabolite	Others
N-Acetylsulfanilamide is a compound with potential anti-infective activity .

HY-178952

Anti-infective agent 12	Bacterial	Infection
Anti-infective agent 12 (Compound A09) is a competitive inhibitor of type I signal peptidease (SPase I), with an IC₅₀ of 4.475 μM and a K_d of 16.3 μM. Anti-infective agent 12 has the ability to disrupt bacterial membranes and remove biofilms. Anti-infective agent 12 exhibits potent bactericidal activity against Gram-positive bacteria, with MIC values of 4, 4, 8, and 8 μg/mL for Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus suis, respectively. Anti-infective agent 12 remains effective against multi-drug resistant strains, but has weaker activity against Gram-negative bacteria (such as Escherichia coli and Salmonella), with MIC values > 64 μg/mL. Anti-infective agent 12 has low hemolytic activity and shows significant efficacy in mouse skin infection models .

HY-B1702

Nifuroxime	Fungal	Infection
Nifuroxime is an anti-infective agent. Nifuroxime can be used in the research of fungal infections .

HY-133719

Fenfuram	Fungal	Infection
Fenfuram is an antifungal agent with an EC₅₀ of 6.18 mg/mL against R. solani. Fenfuram can be used in anti-infective research .

HY-121636S

Resolvin D2-d5 RvD2-d₅	TRP Channel	Infection Neurological Disease Inflammation/Immunology
Resolvin D2-d₅ is the deuterium labeled Resolvin D2. Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC₅₀ = 0.1 nM) and TRPA1 (IC₅₀ = 2 nM) in primary sensory neurons .

HY-178785

Anti-infective agent 11	Parasite	Infection
Anti-infective agent 11 (Compound 19) is an orally active antiparasitic agent. Anti-infective agent 11 inhibits the proteolytic activity of P. falciparum. Anti-infective agent 11 exhibits inhibitory activity against P. falciparum 3D7 with an IC₅₀ of 0.28 μM .

HY-151484

Anti-infective agent 4	Parasite	Infection
Anti-infective agent 4 (compound 73) is an orally active inhibitor of *Trypanosoma cruzi* with an IC₅₀ value of 0.016 μM. Anti-infective agent 4 effectively reduces parasite burden in vivo. Anti-infective agent 4 can be used for the research of infection .

HY-146487

Anti-infective agent 1	Bacterial Parasite	Infection
Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .

HY-151612

Anti-infective agent 6	Parasite	Infection
Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC₅₀=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC₅₀=3.5 μM) .

HY-157840

Anti-infective agent 9	Parasite	Infection
Anti-infective agent 9 (compound 1) is a Plasmodium falciparum inhibitor (IC₅₀=600 nM), can downregulate pyruvate levels and TCA cycle in Plasmodium. Anti-infective agent 9It has good metabolic stability and low toxicity to human liver cells. The study found, Anti-infective agent 9Potential targets for inhibiting Plasmodium falciparum are not 1-deoxidation-d-xylulose-5-Phosphate synthase (DXPS) .

HY-151614

Anti-infective agent 7	Bacterial	Infection
Anti-infective agent 7 is a potent anti-infectious agent. Anti-infective agent 7 has anti-infection activity against P. falciparum (IC₅₀=2.5 μM) and M. tuberculosis (MIC=9 μM) .

HY-161069

Anti-infective agent 8	Bacterial	Infection
Anti-infective agent 8 (compound 9d) is an antibacterial agent with an MIC of 0.5 μg/mL against Staphylococcus aureus and Mycobacterium tuberculosis H37Rv. Anti-infective agent 8 has anti-biofilm activity and significantly reduces Staphylococcus aureus biofilm formation .

HY-146489

Anti-infective agent 3	Bacterial Parasite	Infection
Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL .

HY-146488

Anti-infective agent 2	Parasite Bacterial	Infection
Anti-infective agent 2 (compound 3k) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 0.07 and 2.20 μM, respectively. Anti-infective agent 2 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 32 μg/mL .

HY-172230

Anti-infective agent 10	Virus Protease HCV	Infection
Anti-infective agent 10 (Compound Example 30) is a ns5b polymerase inhibitor that can be used as an anti-HCV agent .

HY-19892

Brilacidin PMX 30063	Bacterial Antibiotic	Infection Cancer
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound .

HY-N11409A

Shikimate-3-phosphate lithium	Herbicide	Others
Shikimate-3-phosphate lithium is the salt form of Shikimate-3-phosphate. Shikimate-3-phosphate lithium is a central microbial, parasite and plant metabolite, as a product of the shikimate kinase-catalysed reaction. Shikimate-3-phosphate lithium serves as an enzyme substrate for 5-enolpyruvoyl-shikimate 3-phosphate synthase, which is a target of anti-infectives and of herbicides .

HY-15034

Indomethacin sodium INDOMETHACIN SODIUM	COX Antibiotic Influenza Virus Bacterial	Inflammation/Immunology Cancer
Indomethacin (Indometacin) sodium is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research. .

HY-P2320

IDR-1	Bacterial	Infection Inflammation/Immunology
IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release .

HY-12687S

Tizoxanide-d4	Isotope-Labeled Compounds Bacterial HIV Autophagy	Infection
Tizoxanide-d₄ is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities .

HY-B2230R

Hinokitiol (Standard) β-Thujaplicin (Standard)	Keap1-Nrf2 DNA Methyltransferase Virus Protease Reference Standards	Infection Cancer
Hinokitiol (Standard) is the analytical standard of Hinokitiol. This product is intended for research and analytical applications. Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

HY-14397G

Indomethacin Indometacin	Antibiotic Influenza Virus Bacterial COX	Inflammation/Immunology Cancer
Indomethacin (GMP) is Indomethacin (HY-14397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

HY-121570

Noxytiolin Noxythiolin	Biochemical Assay Reagents	Infection
Noxytiolin (Noxythiolin) is an *anti-infective* agent and used for irrigation of the peritoneum .

HY-12687R

Tizoxanide (Standard) TIZ (Standard)	Reference Standards Bacterial HIV Autophagy Parasite IKK Influenza Virus	Infection Cancer
Tizoxanide (Standard) is the analytical standard of Tizoxanide. This product is intended for research and analytical applications. Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide *anti-infective* compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has *anti-HIV-1* activities and potent inhibition of both HBV and HCV replication with values EC₅₀ of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .

HY-14882R

Cenicriviroc (Standard) TAK-652 (Standard); TBR-652 (Standard)	CCR HIV Reference Standards	Infection Endocrinology
Cenicriviroc (Standard) is the analytical standard of Cenicriviroc. This product is intended for research and analytical applications. Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity .

HY-135625

BPH-1218	Parasite	Infection
BPH-1218 is an inhibitor of squalene synthase (SQS), with the IC₅₀ of 31 nM and 64 nM for TcSQS and HsSQS, respectively, that can be used as an anti-infective agent .

HY-162113

Antibacterial agent 174	Bacterial	Infection
Antibacterial agent 174 (Compound 5g) is a antibacterial agent. Antibacterial agent 174 has potent anti-infective potential in vivo and appreciable pharmacokinetic profiles. Highly active antibacterial agent 174 has favorable biofilm removal performance, low hemolysis and acceptable mammalian cell toxicity .

Cat. No.	Product Name

HY-L002

Anti-Infection Compound Library

4,310 compounds

An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.

MCE provides a unique collection of 4,310 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.

HY-L254

Bacteria-Sourced Compound Library

61 compounds

Bacteria-derived natural products have long been recognized as an important resource for innovative drug discovery due to their remarkable structural diversity and broad spectrum of biological activities. Microorganisms such as actinomycetes, Bacillus species, and marine bacteria can produce a wide range of small molecules with unique chemical scaffolds, showing extensive application potential in anti-infective, anticancer, immunomodulatory, and metabolic disease research. Many classic drugs, including Streptomycin, Tetracycline, and Doxorubicin, are derived from bacteria-related natural products.

HY-L924

Boronic acid/boronic ester fragment library

1,488 compounds

Boronic acid and boronic ester represent a relatively novel and promising chemical structure in drug design. Boronic acid exists in an sp²-hybridized state, possessing an empty p-orbital that can act as a Lewis acid to accept lone pairs from heteroatoms (O, N, or S). This Lewis acidity enables it to form reversible covalent bonds with amino acid residues such as lysine, serine, threonine, and histidine. Currently, five FDA-approved drugs containing boronic acid or boronic ester predominantly involve such covalent binding mechanisms in their interactions with target proteins. Furthermore, boronic acid can serve as a bioisostere for carboxylic acids, phosphates, and phenolic groups, utilized to improve pharmacokinetic properties and enhance drug efficacy.

To date, five boron-containing drugs have been approved by the FDA. The unique properties of boronic acids and boronic esters confer significant potential in drug design, with applications spanning cancer therapy (e.g., multiple myeloma), anti-infectives (e.g., fungal infections, tuberculosis), anti-inflammatory treatments (e.g., atopic dermatitis), antibacterial agents (e.g., carbapenem-resistant bacterial infections), and Reactive Oxygen Species (ROS)-responsive prodrugs, among others. The MCE Boronic Acid/Boronic Ester Fragment Library, which contains 1,488 compounds, serves as a valuable tool for the development of boron-containing drugs.

Cat. No.	Product Name	Type

HY-14397G

Indomethacin

Indometacin

Fluorescent Dyes

Indomethacin (GMP) is Indomethacin (HY-14397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

Cat. No.	Product Name	Type

HY-14397G

Indomethacin

Indometacin

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Area

HY-P5812

IDR 1002	Integrin	Inflammation/Immunology
IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of β1-integrin, a mechanism that promotes monocyte recruitment .

HY-P2320

IDR-1	Bacterial	Infection Inflammation/Immunology
IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release .

HY-P10547

Macropin MAC-1 peptide	Bacterial	Infection
Macropin (MAC-1 peptide) is an antimicrobial peptide found in the venom of the solitary bee Macropis fulvipes. Macropin has antibacterial activity against both Gram-positive and Gram-negative bacteria, and also exhibits inhibitory activity against fungi and moderate hemolytic activity against human erythrocytes. Macropin can be used in research on anti-infective therapy .

HY-P11242

Cm-CATH2	Bacterial NF-κB p38 MAPK JNK ERK TNF Receptor Interleukin Related	Infection
Cm-CATH2 is an antimicrobial peptide discovered from Chelonia mydas. Cm-CATH2 has a potent, broad-spectrum and rapid bactericidal ability by rapidly destroying the integrity of bacterial cell membranes. It shows strong activity against Gram-positive bacteria (such as VREF, Staphylococcus aureus), Gram-negative bacteria (such as Escherichia coli, Klebsiella pneumoniae), and fungi (such as Candida albicans) with MICs ranges from 1.17 to 18.75 μg/mL. Cm-CATH2 is also effective against various aquatic pathogenic bacteria. Cm-CATH2 not only inhibits biofilm formation but can also remove the formed biofilms. Cm-CATH2 has immunomodulatory functions and chemotactic effects on immune cells, and can inhibit the production of pro-inflammatory cytokines by macrophages stimulated by LPS (HY-D1056). Cm-CATH2 prevents the activation of NF-κB by inhibiting the degradation of IκBα, and also inhibits the phosphorylation of MAPK signaling pathways (p38, JNK, ERK). Cm-CATH2 demonstrates strong anti-infective ability in mouse peritonitis models and pneumonia models .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B2230

Hinokitiol Maximum Cited Publications 8 Publications Verification β-Thujaplicin	Infection Cupressaceae Classification of Application Fields Ketones, Aldehydes, Acids Chamaecyparis obtusa (Siebold & Zucc.) Endl. Plants Disease Research Fields Source Classification	Keap1-Nrf2 DNA Methyltransferase Virus Protease
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

HY-N0808

Camphor 3 Publications Verification (±)-Camphor	Infection Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Plants Lauraceae Cinnamomum camphora Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants TRP Channel Influenza Virus
Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-B1350

Fusidic acid 2 Publications Verification Fusidate; SQ-16603	Infection Triterpenes Microorganisms Classification of Application Fields Terpenoids Disease Research Fields	Bacterial Antibiotic
Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome. Fusidic acid holds promise for research in anticancer and anti-infective applications. .

HY-B1864A

Kasugamycin hydrochloride 1 Publications Verification Ksg hydrochloride	Structural Classification Classification of Application Fields Antibacterial Disease Research Other Antibiotics Biological Pesticide Research Plant agriculture research Agricultural Research Infection Microorganisms Antibiotics Resistance Selection Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Bacterial
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .

HY-N0677A

Kalii Dehydrographolidi Succinas 1 Publications Verification Potassium dehydroandrographolide succinate	Structural Classification Acanthaceae Classification of Application Fields Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification Cancer	Antibiotic
Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate) is an antibiotic. Kalii Dehydrographolidi Succinas exerts immunostimulatory, anti-infective and anti-inflammatory effects . Kalii Dehydrographolidi Succinas shows potential for research on viral pneumonia and viral upper respiratory tract infections .

HY-N0677

Dehydroandrographolide succinate 1 Publications Verification	Acanthaceae Classification of Application Fields Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification Cancer	Influenza Virus Prostaglandin Receptor Akt GSK-3
Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED₅₀ = 386.9 mg/kg) by decreasing TXB₂ levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways .

HY-B0914A

10-Undecenoic acid zinc salt 2 Publications Verification Zinc undecylenate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Fungal Bacterial Amyloid-β Reactive Oxygen Species (ROS) Proteasome
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-N0808R

Camphor (Standard) (±)-Camphor (Standard)	Structural Classification Other Monoterpenes Terpenoids Plants Lauraceae Cinnamomum camphora Source Classification	Reference Standards TRP Channel Influenza Virus
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-B2230R

Hinokitiol (Standard) β-Thujaplicin (Standard)	Structural Classification Cupressaceae Ketones, Aldehydes, Acids Chamaecyparis obtusa (Siebold & Zucc.) Endl. Plants Source Classification	Keap1-Nrf2 DNA Methyltransferase Virus Protease Reference Standards
Hinokitiol (Standard) is the analytical standard of Hinokitiol. This product is intended for research and analytical applications. Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

HY-N13847

Uralsaponin B	Leguminosae Ketones, Aldehydes, Acids Plants Glycyrrhiza uralensis Fisch. Source Classification	Bacterial
Uralsaponin B is classified as an oleanane-type triterpenoid saponin. Uralsaponin B exhibits potential anti-inflammatory and anti-infective activities.

HY-N5197

Dapdiamide A	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Antibiotic
Dapdiamide A is an antibiotic found in Pantoea agglomerans CU0119 strain, exhibiting antibacterial activity and potential applications in anti-infective research .

HY-167641

Malvone A	Malvaceae Quinones Malva sinensis Cav. Plants Naphthalene Quinones Source Classification	Fungal Antibiotic
Malvone A is an antifungal compound found in Malva sylvestris, with an ED₅₀ of 24 μg/mL against V. dahliae. Malvone A may be used for research in the field of anti-infective agents .

HY-136821

Polymyxin D2	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Antibiotic
Polymyxin D2 is an antibiotic discovered from Bacillus polymyxa, exhibiting antibacterial activity. Its core structure consists of a cyclic heptapeptide moiety and a tripeptide side chain with a fatty acyl residue. Polymyxin D2 can be used in anti-infective research .

HY-137323

Leucinostatin H	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Leucinostatin H is a polypeptide antibiotic discovered in Paecilomyces marquandii, characterized by a tertiary amine-oxide terminal group. Leucinostatin H exhibits inhibitory activity against Gram-positive bacteria, such as Bacillus subtilis, B. cereus, and Staphylococcus aureus (MIC 10-100 μg/mL). Leucinostatin H holds potential for research in anti-infective and plant disease control applications .

HY-N14354

Ferrocin B	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Ferrocin B is an iron-containing cyclic decapeptide antibiotic found in the bacterium Pseudomonas fluorescens YK-310, exhibiting strong antibacterial activity primarily against Gram-negative bacteria, with particularly potent inhibitory effects on Pseudomonas aeruginosa. In a mouse infection model, Ferrocin B shows a half effective dose (ED₅₀) of 0.593 mg/kg against P. aeruginosa. Ferrocin B holds potential for research in the field of anti-infective therapies .

HY-B1864AR

Kasugamycin hydrochloride (Standard) Ksg hydrochloride (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Antibacterial Disease Research Other Antibiotics Plant agriculture research Source Classification	Reference Standards Antibiotic Bacterial
Kasugamycin (Ksg) hydrochloride (Standard) is the analytical standard of Kasugamycin hydrochloride (HY-B1864A). This product is intended for research and analytical applications. Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .

HY-161935

6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid	Lysimachia tengyuehensis Hand.-Mazz. Antibiotics Plants Primulaceae Other Antibiotics Source Classification	Bacterial
6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid (Compound 2) exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin enterococci (VRE). 6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid interfers with the integrity and function of the bacterial cell membrane, and affects metabolism in MRSA. 6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid exhibits anti-inflammatory and anti-infective efficacy, and promotes angiogenesis in mice .

HY-B0914AR

10-Undecenoic acid zinc salt (Standard) Zinc undecylenate (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Reference Standards Fungal Amyloid-β Reactive Oxygen Species (ROS) Proteasome Bacterial
10-Undecenoic acid (zinc salt) (Standard) is the analytical standard of 10-Undecenoic acid (zinc salt). This product is intended for research and analytical applications. 10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-N19859

Everlastoside C Milliettiioside	Structural Classification Myroxylon balsamum (L.) Harms Plants Compositae Saccharides Monosaccharides Source Classification	Others
Everlastoside C (Milliettiioside) (Compound 3) is a glycoside that can be found in the flowers of Helichrysum arenarium. Glycosidic compounds typically possess anti-inflammatory, anti-infective, anti-cancer, and antioxidant properties, playing a variety of important roles within biological organisms .

Cat. No.	Product Name	Chemical Structure

HY-121636S

Resolvin D2-d5
Resolvin D2-d₅ is the deuterium labeled Resolvin D2. Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC₅₀ = 0.1 nM) and TRPA1 (IC₅₀ = 2 nM) in primary sensory neurons .

HY-12687S

Tizoxanide-d4
Tizoxanide-d₄ is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities .

HY-14397S2

Indometacin-d7
Indometacin-d₇ is deuterated labeled Indomethacin (HY-14397). Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

HY-14397S3

Indomethacin-13C6
Indomethacin- ¹³C₆ (Indometacin- ¹³C₆) is ¹³C labeled Indomethacin. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

HY-W069721S

N-Acetylsulfanilamide-d4
N-Acetylsulfanilamide-d₄ (4-Acetamidobenzenesulfonamide-d₄) is a deuterium labeled N-Acetylsulfanilamide (HY-W069721). N-Acetylsulfanilamide is a compound with potential anti-infective activity .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14397G

Indomethacin Indometacin	Antibiotic Influenza Virus Bacterial COX	Inflammation/Immunology Cancer
Indomethacin (GMP) is Indomethacin (HY-14397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .

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