18 Results for "

Aqp1

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Aqp1" in MCE Product Catalog:

2
2 Cited Publications
製品番号: HY-110200
CAS 番号: 37710-81-9
純度:  98.51%
別名: m-Phenylenediacrylic acid; m-Benzenediacrylic acid
Target:  

Aquaporin

研究分野:  

Metabolic Disease Cancer

TC AQP1 1 (m-Phenylenediacrylic acid) is a potent AQP1 inhibitor. TC AQP1 1 inhibits AQP1-mediated water flux in oocytes, with an IC50 of 8 μM [1].
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2
2 Cited Publications
製品番号: HY-N6016
CAS 番号: 382146-66-9
Bacopaside II, an extract from the medicinal herb Bacopa monnieri. Bacopaside II is the inhibitor for AQP1 that exhibits anti-angiogenesis activity. Bacopaside II exhibits cytotoxicity and induces apoptosis in cancer cells [1] .
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1
1 Cited Publications
製品番号: HY-N2013
CAS 番号: 13395-02-3
別名: Aristololactam; Aristolactam
Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis [1] .
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製品番号: HY-174166
CAS 番号: 1021869-59-9
Target:  

Aquaporin

研究分野:  

Metabolic Disease

AqF026 is an aquaporin 1 (AQP1) agonist. AqF026 enhances the channel activity of human AQP1 in the Xenopus laevis oocyte system. AqF026 enhances the osmotic transport of water across the peritoneum in a mouse model of peritoneal dialysis. AqF026 can be used in studies related to ultrafiltration failure in peritoneal dialysis [1] .
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製品番号: HY-N4246
CAS 番号: 382148-47-2
Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP-gated ion channel activities of AQP1 without affecting AQP4, thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K, specifically inhibits MAO-A, effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II (HY-N6016), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor (PXR). Bacopaside I is applicable to the research of colon cancer, breast cancer, vascular dementia, cerebral ischemia and other related diseases [1] .
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製品番号: HY-RS00871
研究分野:  

Others

AQP1 Human Pre-designed siRNA Set A contains three designed siRNAs for AQP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS17735
研究分野:  

Others

Aqp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Aqp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS24200
研究分野:  

Others

Aqp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Aqp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-110200R
CAS 番号: 37710-81-9
別名: m-Phenylenediacrylic acid (Standard); m-Benzenediacrylic acid (Standard)
研究分野:  

Metabolic Disease Cancer

TC AQP1 1 (Standard) is the analytical standard of TC AQP1 1 (HY-110200). This product is intended for research and analytical applications. TC AQP1 1 (m-Phenylenediacrylic acid) is a potent AQP1 inhibitor. TC AQP1 1 inhibits AQP1-mediated water flux in oocytes, with an IC50 of 8 μM [1].
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製品番号: HY-N6016R
CAS 番号: 382146-66-9
Bacopaside II (Standard) is the analytical standard of Bacopaside II. This product is intended for research and analytical applications. Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis [1] .
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製品番号: HY-N4246R
CAS 番号: 382148-47-2
Bacopaside I (Standard) is the analytical standard of Bacopaside I. This product is intended for research and analytical applications. Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP-gated ion channel activities of AQP1 without affecting AQP4, thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K, specifically inhibits MAO-A, effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II (HY-N6016), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor (PXR). Bacopaside I is applicable to the research of colon cancer, breast cancer, vascular dementia, cerebral ischemia and other related diseases [1] .
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製品番号: HY-N2013R
CAS 番号: 13395-02-3
別名: Aristololactam (Standard); Aristolactam (Standard)
Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis [1] .
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製品番号: HY-P87817

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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製品番号: HY-P72086
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: Aqp1; Aquaporin 1 (Channel-Forming Integral Protein, 28kDa); Prev. CO; Aquaporin 1, Colton Blood Group Antigen; CHIP28; Aquaporin 1 Splice Variant 2; Aquaporin-CHIP; Colton Blood Group Antigen; Aquaporin-1; Bloodgroup CO Protein; Aquaporin 1 (Channel-Form
Species:  
Human
Source:  
E. coli
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製品番号: HY-P72085
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: Aqp1; Aquaporin 1 (Channel-Forming Integral Protein, 28kDa); Prev. CO; Aquaporin 1, Colton Blood Group Antigen; CHIP28; Aquaporin 1 Splice Variant 2; Aquaporin-CHIP; Colton Blood Group Antigen; Aquaporin-1; Bloodgroup CO Protein; Aquaporin 1 (Channel-Form
Species:  
Human
Source:  
E. coli
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製品番号: HY-P81404A
別名: Aqp1; CHIP28; Aquaporin-1; Aqp-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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製品番号: HY-P81404
別名: Aqp1; CHIP28; Aquaporin-1; Aqp-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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製品番号: HY-P86699
別名: Aqp 1; Aqp-1; Aqp1_HUMAN; Aquaporin-1; Aquaporin-CHIP; Channel like integral membrane protein 28 kDa; MGC26324; Water channel protein CHIP 29; Aqp CHIP; Aqp1; Aquaporin CHIP; Aquaporin1; Aquaporin 1; Channel forming integral protein 28kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; Urine water channel; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule.

Host:  

Rabbit

Application:  

WB, IF-Tissue, IHC-P, IHC-F

Reactivity:  

Human, Mouse, Rat

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