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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Arg513
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Arg513" in MCE Product Catalog:
Cat. No.: HY-184709
Target:
Research Areas:
COX-2-IN-69 is a selective, orally active COX-2 inhibitor with an IC50 of 0.82 μM. COX-2-IN-69 occupies the secondary pocket of COX-2, interacts with His90 and Arg513, and reduces the serum levels of PGE2, IL-1β and TNF-α. COX-2-IN-69 exerts anti-inflammatory activity in a rat paw edema model. COX-2-IN-69 can be used in inflammation-related research .
Cat. No.: HY-184710
Research Areas:
COX-2-IN-69 is a selective, orally active COX-2 inhibitor with an IC50 of 0.90 μM. COX-2-IN-69 occupies the secondary pocket of COX-2, interacts with His90 and Arg513, and reduces serum levels of PGE2, IL-1β and TNF-α. COX-2-IN-69 exerts anti-inflammatory activity in a rat paw swelling model. COX-2-IN-69 can be used in inflammation-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
