1 Result for "

BF-158

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BF-158" in MCE Product Catalog:

Cat. No.: HY-167189
CAS No.: 682763-67-3
Target:  

Tau Protein Amyloid-β

Domaines de recherche:  

Neurological Disease

BF-158 is a quinoline-based Tau Protein fluorescent imaging probe that produces specific staining by recognizing the β-sheet structure of paired helical filaments (PHF)/neurofibrillary tangles (NFT) in tau aggregates, with EC50 values of 399 nM and 659 nM for tau fibrils and Aβ1-42 fibrils, respectively. BF-158 preferentially labels NFTs, neuropil threads, and PHF-type neurites. BF-158 is useful for the study and imaging of tau pathology in Alzheimer's disease .
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