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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
BTR2000
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "BTR2000" in MCE Product Catalog:
Cat. No.: HY-172563
Target:
Research Areas:
BTR2000, a specifically KLHL20 ligand, is capable of binding to the KLHL20 Kelch domain with high affinity. BTR2000 can be used as a ligand for E3 ligase for the synthesis of BTR2004 (HY-172562) .
Cat. No.: HY-172563A
Target:
Research Areas:
BTR2000 TFA, a specifically KLHL20 ligand, is capable of binding to the KLHL20 Kelch domain with high affinity. BTR2000 TFA can be used as a ligand for E3 ligase for the synthesis of BTR2004 (HY-172562) .
Cat. No.: HY-172564
Research Areas:
BTR2000-Gly-Gly-Gly is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004 (HY-172562) .
Cat. No.: HY-172564A
Research Areas:
BTR2000-Gly-Gly-Gly TFA is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004 (HY-172562) .
Cat. No.: HY-178043
Target:
Research Areas:
BTR2038 is a BTR2000-based heterobifunctional PROTAC that induces the degradation of BRD9 by recruiting the CUL3 KLHL20 E3 ubiquitin ligase. BTR2038 consists of a BRD9 bromodomain ligand derived from a BI-7273 analog, a linker, and the macrocyclic KLHL20 ligand BTR2000. BTR2038 is applicable for research related to KLHL20-recruited targeted protein degradation and BRD9 modulation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
