1 Result for "

CBPD 409

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "CBPD 409" in MCE Product Catalog:

Art. -Nr.: HY-158113
CAS. Nr.: 3037549-86-0
Forschungsgebiete:  

Cancer

CBPD-409 is an orally active PROTAC degrader for CBP/p300, with DC50 of 0.2–0.4 nM. CBPD-409 exhibits antiproliferative effects in AR+ prostate cancer cell lines VCaP, LNCaP and 22Rv1, with IC50s of 1.2–2.0 nM. CBPD-409 exhibits antitumor efficacy (Red: CBP inhibitor GNE049 (HY-108435); Blue: CRBN/cullin 4A Thalidomide (HY-14658); Black: Linker) .
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