1 Result for "

CFT 1297

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "CFT 1297" in MCE Product Catalog:

Cat. No.: HY-168546
CAS No.: 2154353-03-2
Research Areas:  

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CFT-1297 is a CRBN-recruiting BRD4 PROTAC degrader with a DC50 of 5 nM; it has KD values of 2.1 μM, 0.68 μM and 58 nM for CRBN, BRD4 (BD2) and BRD4 (BD1), respectively. CFT-1297 binds weakly to CRBN-DDB1, with a KD value of 2.1 μM .
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