2 Results for "

CGP 48933 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CGP 48933 (Standard)" in MCE Product Catalog:

Cat. No.: HY-18204R
CAS No.: 137862-53-4
Synonyms: CGP 48933 (Standard)
Valsartan (Standard) is the analytical standard of Valsartan. This product is intended for research and analytical applications. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research .
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Cat. No.: HY-W414915R
CAS No.: 137863-17-3
Synonyms: CGP 48933 methyl ester (Standard)
Valsartan (CGP 48933) methyl ester (Standard) is the analytical standard of Valsartan methyl ester (HY-W414915). This product is intended for research and analytical applications. Valsartan methyl ester is the methyl ester derivative of Valsartan (HY-18204). Valsartan is a selective angiotensin II type 1 (AT1) receptor blocker (ARB) with potent antihypertensive and cardioprotective effects. Valsartan competitively binds to AT1 receptors, inhibiting the binding of angiotensin II to AT1 receptors, thereby blocking angiotensin II-mediated vasoconstriction, sodium retention, and myocardial hypertrophy signaling pathways. Valsartan reduces systolic blood pressure in L-NAME-induced hypertensive rats. Valsartan can be used for the study and treatment of arterial hypertension, hypertensive heart disease, and heart failure .
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