Valsartan methyl ester (Standard)

(Synonyms: CGP 48933 methyl ester (Standard))

Valsartan (CGP 48933) methyl ester (Standard) is the analytical standard of Valsartan methyl ester (HY-W414915). This product is intended for research and analytical applications. Valsartan methyl ester is the methyl ester derivative of Valsartan (HY-18204). Valsartan is a selective angiotensin II type 1 (AT1) receptor blocker (ARB) with potent antihypertensive and cardioprotective effects. Valsartan competitively binds to AT1 receptors, inhibiting the binding of angiotensin II to AT1 receptors, thereby blocking angiotensin II-mediated vasoconstriction, sodium retention, and myocardial hypertrophy signaling pathways. Valsartan reduces systolic blood pressure in L-NAME-induced hypertensive rats. Valsartan can be used for the study and treatment of arterial hypertension, hypertensive heart disease, and heart failure.

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  • Pureté : 98%
  • CAS No.: 137863-17-3
  • Formule: C25H31N5O3
  • Masse moléculaire:449.55
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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