2 Results for "

CL-5343

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CL-5343" in MCE Product Catalog:

Referencia número: HY-W074975
No. CAS: 14949-00-9
Synonyms: 5-Amino-1,3,4-thiadiazole-2-sulfonamide
Target:  

Carbonic Anhydrase

Áreas de investigación:  

Cancer

CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is a selective inhibitor of carbonic anhydrase B (HCA-B) and isoforms I, II, IV, and VII. CL 5343 has a Ki of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer .
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Referencia número: HY-W074975R
No. CAS: 14949-00-9
Synonyms: 5-Amino-1,3,4-thiadiazole-2-sulfonamide (Standard)
Áreas de investigación:  

Cancer

CL 5343 (Standard) is the analytical standard of CL 5343. This product is intended for research and analytical applications. CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is an inhibitor of human carbonic anhydrase B (HCA-B). CL 5343 can serve as a CA9 ligand to achieve the targeted delivery of maytansinoid to the cell membrane of SKRC52 renal cancer cells .
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