2 Results for "

CP734432

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CP734432" in MCE Product Catalog:

Cat. No.: HY-119236
CAS No.: 431990-08-8
Synonyms: CP-734432
CP-432 (CP-734432) is a EP4 receptor agonist with an IC50 of 2 nM for human sources, 8 nM for canine sources, and an EC50 of 1 nM for human sources. CP-432 stimulates cAMP production and activates β-lactamase (β-lactamase) activity via the cAMP response element signaling pathway. CP-432 is applicable to research related to glaucoma .
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Cat. No.: HY-185643
CAS No.: 1201925-19-0
Research Areas:  

Neurological Disease

PF-04475270 is a prodrug of CP-734432 (HY-119236), as well as an agonist of the EP4 prostaglandin receptor, with IC50 values of 2 nM and 8 nM against human and canine sources, respectively. PF-04475270 is rapidly hydrolyzed into its active metabolite CP-734432 by ocular esterases or corneal homogenate, stimulates cAMP production, and activates cAMP response element-mediated β-lactamase activity in cells expressing EP4. PF-04475270 can be used in research related to glaucoma .
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