1 Result for "

CSF1R-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CSF1R-IN-3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-139990
CAS No.: 2760584-90-3
Purity:  98.26%
Target:  

c-Fms

Research Areas:  

Cancer

CSF1R-IN-3 (compound 21) is a potent and orally active CSF-1R inhibitor (IC50=2.1 nM). CSF1R-IN-3 is a potent antiproliferative activity against colorectal cancer cells. CSF1R-IN-3 inhibits the progression of colorectal cancer by suppressing the migration of macrophages, reprograming M2-like macrophages to the M1 phenotype, and enhancing the antitumor immunity .
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