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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
CTM
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "CTM" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: NX-5948; BTK-IN-24
Research Areas:
Bexobrutideg (NX-5948) is an orally active chimeric targeting molecule (CTM) that induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. Bexobrutideg mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. Bexobrutideg exhibits potent tumor growth inhibition in TMD8 xenograft models that contain either wild-type BTK or BTKi-resistant mutations. Bexobrutideg is efficacious in a mouse collageninduced arthritis (CIA) model. Bexobrutideg can cross the blood brain barrier (BBB). Bexobrutideg is a PROTAC composed of the ligand for target protein, a linker, and a cereblon E3 ligase (CRBN) complex (Red: BTK ligand (HY-170324); Blue: CRBN ligand (HY-171893); Black: linker) .
Cat. No.: HY-A0110A
CAS No.: 95789-30-3
Synonyms: CTM-HE hydrochloride; SCE-2174 hydrochloride
Target:
Research Areas:
Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic .
Cat. No.: HY-P991608
Synonyms: 7F11C7
Cat. No.: HY-A0110AR
CAS No.: 95789-30-3
Synonyms: CTM-HE hydrochloride (Standard); SCE-2174 hydrochloride (Standard)
Target:
Research Areas:
Cefotiam hexetil (hydrochloride) (Standard) is the analytical standard of Cefotiam hexetil (hydrochloride). This product is intended for research and analytical applications. Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic[1].
Cat. No.: HY-RS06411
Target:
Research Areas:
HSF4 Human Pre-designed siRNA Set A contains three designed siRNAs for HSF4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20517
Target:
Research Areas:
Vsig2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vsig2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
