Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
CW 2
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "CW 2" in MCE Product Catalog:
Referencia número: HY-173437
Target:
Áreas de investigación:
CW-2 is a PARP1 PROTAC degrader. CW-2 has potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and CDDP-resistant cells (A549/CDDP: IC50 = 3.52 μM). CW-2 has synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts antitumor effects by inducing DNA damage, impairing DNA repair, and activating mitochondria-dependent apoptosis (Pink: PARP1 ligand (HY-173441); Blue: E3 CRBN ligand (HY-173439); Black: linker (HY-173440)) .
Referencia número: HY-173439
No. CAS: 2387496-31-1
Target:
Áreas de investigación:
CRBN ligand-907 is a CRBN ligand, which can be used for the synthesis of PROTACs, such as CW-2 (HY-173437) .
Referencia número: HY-173441
No. CAS: 3088771-63-2
Áreas de investigación:
PARP1 ligand-1 is a PARP1 ligand, which can be used for the synthesis of PROTACs, such as CW-2 (HY-173437) .
Referencia número: HY-173442
No. CAS: 3114223-14-9
Áreas de investigación:
PARP1 Ligand-linker Conjugate-1 is a PARP1 ligand-linker conjugate that can be used for the synthesis of PROTACs, such as CW-2 (HY-173437) .
Referencia número: HY-173440
No. CAS: 3114223-12-7
Target:
Áreas de investigación:
Methyl 2-(2-aminoacetamido)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate is a PROTAC linker that can be used for the synthesis of PROTACs, such as CW-2 (HY-173437) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
