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Cat. No.: HY-173442

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PARP1 Ligand-linker Conjugate-1

PARP1 Ligand-linker Conjugate-1 is a PARP1 ligand-linker conjugate that can be used for the synthesis of PROTACs, such as CW-2 (HY-173437).

For research use only. We do not sell to patients.

CAS No.: 3114223-14-9
Formula: C₃₁H₂₇FN₄O₆
Molecular Weight:570.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PARP1 Ligand-linker Conjugate-1 Chemical Structure

CAS No.: 3114223-14-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PARP1 Ligand-linker Conjugate-1 is a PARP1 ligand-linker conjugate that can be used for the synthesis of PROTACs, such as CW-2 (HY-173437)^[1].

All PARP Isoforms :

Chemical Information

CAS No. 3114223-14-9
Molecular Weight 570.57
Formula C₃₁H₂₇FN₄O₆
SMILES

O=C1NN=C(C2=CC=CC=C21)CC3=CC(F)=C(C=C3)C(NCC(NC(CC4=CC=C(C=C4)OCC#C)C(OC)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li CX, et al. Pt(IV)-PROTAC Complexes with Synergistic Antitumor Activity and Enhanced Membrane Permeability. J Med Chem. 2025 Apr 24;68(8):8208-8225. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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PARP1 Ligand-linker Conjugate-1

All PARP Isoforms