1 Result for "

CWHM117

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CWHM117" in MCE Product Catalog:

Cat. No.: HY-188134
CAS No.: 1505452-80-1
Target:  

Parasite Proteasome

Research Areas:  

Infection

CWHM-117 is an orally active aspartic protease inhibitor with selective activity against Toxoplasma gondii. CWHM-117 inhibits the proliferation of Toxoplasma gondii tachyzoites in human fibroblasts, with an EC50 of 2.00 µM. CWHM-117 delays mortality in an acute mouse model of toxoplasmosis. In a chronic mouse model of toxoplasmosis, CWHM-117 reduces brain cyst burden and prolongs survival. CWHM-117 can be used for research on toxoplasmosis .
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