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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Caki
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Caki" in MCE Product Catalog:
Cat. No.: HY-161865
Antitumor agent-180 (Compound 13a) is an inhibitor for BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B). Antitumor agent-180 inhibits the proliferation of ccRCC cell Caki-1 with IC50 of 2.047 µM. Antitumor agent-180 induces necrosis and apoptosis in Caki-1 .
Cat. No.: HY-172089
CAS No.: 3105969-02-3
TG101209 analog 1 (Compound 8h) is an inhibitor for BUB1B with an IC50 of 10.36 μM. TG101209 analog 1 exhibits cytotoxicity (IC50 for Caki-1 is 1.347 μM), induce necrosis and apoptosis .
Cat. No.: HY-165284
CAS No.: 1370652-56-4
Research Areas:
CM-118 is a potent and selective c-Met and ALK inhibitor. CM-118 inhibits the HGF-induced c-Met phosphorylation. CM-118 inhibits phosphorylation of ALK, EML4-ALKv1, ALK F1174L, and EMl4-ALKv1 L1196M, with respective IC50 values 0.92, 1.25, 1.9, and 3.5 μM. CM-118 exhibits anticancer activity against cancers dependent on the c-Met or ALK oncogenic pathways .
Cat. No.: HY-137632
CAS No.: 142754-28-7
Sp-8-Cl-cAMPS is an analog of cAMP (HY-B1511) and a derivative of Sp-8-Cl-cAMP. Sp-8-Cl-cAMPS inhibits the growth of human leukemia cell HL-60 and colon cancer cell LS-174T, with IC50 of 8-100 μM. Sp-8-Cl-cAMPS activates the protein kinases cAKI and cAKII, with Ka of 0.25 and 3.2 μM .
Cat. No.: HY-P86799
Synonyms: CAGH39 antibody; Caki antibody; Calcium/calmodulin dependent serine protein kinase antibody; Calcium/calmodulin dependent serine protein kinase (MAGUK family) antibody; Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase antibody; Calcium/calmodulin-dependent serine protein kinase antibody; CAMGUK antibody; CAMGUK protein antibody; CAMGUK, drosophila, homolog of antibody; casK antibody; CAGH39 antibody; Caki antibody; Calcium/calmodulin dependent serine protein kinase antibody; Calcium/calmodulin dependent serine protein kinase (MAGUK family) antibody; Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase antibody; Calcium/calmodulin-dependent serine protein kinase antibody; CAMGUK antibody; CAMGUK protein antibody; CAMGUK, drosophila, homolog of antibody; casK antibody; CMG antibody; CSKP_HUMAN antibody; DXPri1 antibody; DXRib1 antibody; FGS4 antibody; FLJ22219 antibody; FLJ31914 antibody; hCASK antibody; LIN 2 antibody; Lin 2 homolog antibody; LIN2 antibody; Lin2 homolog antibody; MICPCH antibody; MRXSNA antibody; Pals3 antibody; Peripheral plasma membrane protein CASK antibody; Protein lin-2 homolog antibody; TNRC8 antibody; Trinucleotide repeat containing 8 antibody; Vertebtate LIN2 homolog antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
