Sp-8-Cl-cAMPS
Sp-8-Cl-cAMPS is an analog of cAMP (HY-B1511) and a derivative of Sp-8-Cl-cAMP. Sp-8-Cl-cAMPS inhibits the growth of human leukemia cell HL-60 and colon cancer cell LS-174T, with IC50 of 8-100 μM. Sp-8-Cl-cAMPS activates the protein kinases cAKI and cAKII, with Ka of 0.25 and 3.2 μM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 142754-28-7
- 分子式: C10H11ClN5O5PS
- 分子量:379.72
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-B0764
Bucladesine sodiumcAMP Analog -
HY-12306
8-Bromo-cAMP sodium saltPKA Activator -
HY-101379A
8-Bromo-cGMP sodiumPKG Activator -
HY-111673
8-CPT-Cyclic AMP sodiumPKA Activator -
HY-103322
6-Bnz-cAMP sodium saltPKA Activator -
HY-113469A
Cyclic GMP sodiumSecond Messenger -
HY-123396
8-Chloro-cAMPcAMP Analogue -
HY-B0764R
Bucladesine sodium (Standard)cAMP Analog -
HY-100530
Rp-cAMPS triethylammonium saltPKA I/II Antagonist -
HY-107544
8-pCPT-2'-O-Me-cAMP-AMAMP Analogue -
HY-B0764B
BucladesineCAMP Analog -
HY-B0764G
Bucladesine sodium (GMP)PKA activator
生物活性
製品説明
化学情報
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CAS 番号 142754-28-7
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分子量 379.72
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分子式 C10H11ClN5O5PS
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SMILES
S[P@@]1(O[C@H]2[C@@H](O)[C@H](N3C(Cl)=NC4=C3N=CN=C4N)O[C@@H]2CO1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Sp-8-Cl-cAMPS 関連分類
HY-137632 関連分類
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