TG101209 analog 1
Based on 1 Customer Validation
TG101209 analog 1 (Compound 8h) is an inhibitor for BUB1B with an IC50 of 10.36 μM. TG101209 analog 1 exhibits cytotoxicity (IC50 for Caki-1 is 1.347 μM), induce necrosis and apoptosis.
For research use only. We do not sell to patients.
- Purity: 98.27%
- CAS No.: 3105969-02-3
- Formula: C24H31N5O5S
- Molecular Weight:501.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 3105969-02-3
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Appearance Solid
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Molecular Weight 501.60
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Formula C24H31N5O5S
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Color White to off-white
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SMILES
O=S(C1=CC=CC(NC2=NC(NC3=CC(OC)=C(OC)C(OC)=C3)=NC=C2C)=C1)(NC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 350 mg/mL (697.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9936 mL | 9.9681 mL | 19.9362 mL | 49.8405 mL |
| 5 mM | 0.3987 mL | 1.9936 mL | 3.9872 mL | 9.9681 mL | |
| 10 mM | 0.1994 mL | 0.9968 mL | 1.9936 mL | 4.9841 mL | |
| 15 mM | 0.1329 mL | 0.6645 mL | 1.3291 mL | 3.3227 mL | |
| 20 mM | 0.0997 mL | 0.4984 mL | 0.9968 mL | 2.4920 mL | |
| 25 mM | 0.0797 mL | 0.3987 mL | 0.7974 mL | 1.9936 mL | |
| 30 mM | 0.0665 mL | 0.3323 mL | 0.6645 mL | 1.6614 mL | |
| 40 mM | 0.0498 mL | 0.2492 mL | 0.4984 mL | 1.2460 mL | |
| 50 mM | 0.0399 mL | 0.1994 mL | 0.3987 mL | 0.9968 mL | |
| 60 mM | 0.0332 mL | 0.1661 mL | 0.3323 mL | 0.8307 mL | |
| 80 mM | 0.0249 mL | 0.1246 mL | 0.2492 mL | 0.6230 mL | |
| 100 mM | 0.0199 mL | 0.0997 mL | 0.1994 mL | 0.4984 mL |