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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Candida isolates
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Candida isolates" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P11191
CAS No.: 590424-23-0
Cat. No.: HY-155545
Antifungal agent 60 (compound 16) is an inhibitor of ergosterol biosynthesis with broad-spectrum antifungal activity. Antifungal agent 60 inhibits 7 human pathogenic fungal species, 2 fluconazole-resistant C. albicans isolates and 2 multi-drug resistant Candida auris isolates. Antifungal agent 60 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-113863
CAS No.: 104153-37-9
Synonyms: HOE 351
Rilopirox (HOE 351) is a hydroxy-pyridone compound with antimycotic properties. Rilopirox, a chelating agent, can inhibit catalase. Rilopirox inhibits the respiratory chain. Rilopirox inhibits growth of yeast isolates with a MIC50 of 4 μg/mL. Rilopirox has the potential for vaginal candidosis and oropharyngeal Candida infections research .
Cat. No.: HY-138074
CAS No.: 93074-04-5
Synonyms: 5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime
Milbemycin A4 oxime (5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime) is a derivative of Milbemycin A4 (HY-126906) and a component of Milbemycin oxime (HY-B0778), both of which have insecticidal and nematicidal activities. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae in naturally infected dogs with D. immitis and inhibits the growth of clinical isolates of Candida glabrata (MIC80=16-32 μg/mL). Milbemycin A4 oxime (2.5 μg/mL) blocks the efflux of Fluconazole (HY-B0101) from clinical isolates of Candida glabrata. Milbemycin A4 oxime enhances doxorubicin-induced cell growth inhibition and increases the intracellular accumulation of doxorubicin and P-glycoprotein substrate Rhodamine 123 (HY-D0816) in doxorubicin-resistant but not sensitive MCF-7 breast cancer cells in a concentration-dependent manner.
Cat. No.: HY-183872
CAS No.: 851075-79-1
Target:
Domaines de recherche:
FTR1335 is an Antifungal agent as well as a selective, substrate peptide-competitive, and myristoyl-CoA non-competitive inhibitor of N-myristoyltransferase CaNmt, with an IC50 of 0.49 nM against Candida albicans CaNmt. FTR1335 exhibits fungicidal activity against Candida albicans and inhibits the growth of Candida tropicalis. FTR1335 can be used in research related to Candida albicans infections .
Cat. No.: HY-N18360
CAS No.: 66081-38-7
Synonyms: Tunicamycin 17:1
Target:
Cat. No.: HY-N19799
CAS No.: 1464778-45-7
Category:
Target:
Cat. No.: HY-118707
CAS No.: 14486-15-8
Synonyms: Met-met-met
Target:
Domaines de recherche:
Trimethionine (Met-met-met) is an orally active tripeptide substrate of peptide transport systems. Trimethionine interacts with the triple-leucine-triple-threonine transport system and the oligopeptide permease (Opp) system in Escherichia coli, competing for uptake and transport processes. Trimethionine antagonizes the toxicity of threonine tripeptide and ornithine tripeptide, and competes with peptide-supported growth and amino acid source utilization processes in Escherichia coli strains. Trimethionine is taken up by Candida albicans via a carrier-mediated, energy-dependent manner, and is subsequently hydrolyzed into free methionine intracellularly. Trimethionine can be used in studies related to Candida albicans infections .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
