75 Results for "

Carcinoembryonic antigen

" in MedChemExpress (MCE) Product Catalog:
Products (75)

75 Results for "Carcinoembryonic antigen" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99011
CAS No.: 1855925-27-7
Synonyms: RG-7802; RO-6958688; CEA-TCB

Target:  

CD3

Research Areas:  

Cancer

Cibisatamab, a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab can be used for colorectal cancer research .
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2
2 Cited Publications
Cat. No.: HY-P99051
CAS No.: 2226224-30-0
Synonyms: BAY 1834942
Tinurilimab (Bay 1834942) is an anti-CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6) humanized IgG2 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors. Tinurilimab shows an increased tumor cell killing effect in the tumor-cell/T-cell co-culture system .
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2
2 Cited Publications
Cat. No.: HY-P70675
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM5; Cell Adhesion Molecule CEACAM5; Prev. CEA; Meconium antigen 100; Carcinoembryonic antigen-Related Cell Adhesion Molecule 5; Carcinoembryonic antigen-Related Cell Adhesion Molecule 5 Isoform 5D; CD66e; Carcinoembryonic antigen-Related Cell Adhesio
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P78397
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CEACAM6; Cell Adhesion Molecule CEACAM6; Prev. NCA; Carcinoembryonic antigen-Related Cell Adhesion Molecule 6; NCA-50/90; Non-Specific Crossreacting antigen; CD66c; Cluster Of Differentiation 66c; Carcinoembryonic antigen-Related Cell Adhesion Molecule 6
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P99160
CAS No.: 219649-07-7
Synonyms: hMN14

Research Areas:  

Cancer

Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy .
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Cat. No.: HY-177434
CAS No.: 2873366-83-5
Synonyms: Precem-TcT; M 9140
Precemtabart tocentecan (Precem-TcT; M 9140) is an anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody-drug conjugate (ADC). Precemtabart tocentecan consists of a tumor-specific anti-CEACAM5 monoclonal antibody Precemtabart (HY-P990940), a highly hydrophilic and stable cleavable β-glucuronide linker, and a topoisomerase 1 inhibitor payload Exatecan (HY-13631), and the drug-linker conjugate for ADC is Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179). Precemtabart tocentecan inhibits the growth of CEACAM5-positive cancer cells. Precemtabart tocentecan exhibits significant antitumor activity in CEACAM5-expressing xenograft models. Precemtabart tocentecan can be used for the study of CEACAM5-expressing advanced solid tumors, especially mCRC .
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Cat. No.: HY-P0277
CAS No.: 168635-85-6
Synonyms: CEA peptide
Carcinoembryonic antigen peptide 1 (CEA peptide) is a 9-amino acid HLA-A0201-binding cytotoxic T lymphocyte (CTL) epitope peptide derived from carcinoembryonic antigen (CEA). The IC50 of Carcinoembryonic antigen peptide 1 binding to HLA-A0201 is 2 μM. Carcinoembryonic antigen peptide 1 binds to HLA-A0201 to form a peptide-MHC I complex, which is recognized by the T cell receptor (TCR) of CAP1-specific CD8 + CTLs, thereby inducing antigen-specific T cell activation, IFN-γ production, and CTL-mediated lysis of target cells. Carcinoembryonic antigen peptide 1 is used in research on CEA-specific CTL responses and colorectal cancer .
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Cat. No.: HY-P99498
CAS No.: 1509916-03-3
Synonyms: CEA-IL2v; RG 7813; RO 6895882

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Cergutuzumab amunaleukin (CEA-IL2v) is a monomeric carcinoembryonic antigen (CEA)-targeted IL-2 variant-based immunocytokine. Cergutuzumab amunaleukin has immunostimulating and antineoplastic activities .
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Cat. No.: HY-P991060
CAS No.: 1622305-37-6

Research Areas:  

Cancer

Cergutuzumab is a fully human IgG1 antibody that targets carcinoembryonic antigen (CEA, CEACAM5, CD66e). Cergutuzumab can be used to form the recombinant protein Cergutuzumab amunaleukin (HY-P99498) .
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Cat. No.: HY-P990821

Target:  

Tim3

Research Areas:  

Inflammation/Immunology

Anti-Mouse TIM-3 Antibody (RMT3-23) is a kind of rat-derived anti-mouse TIM-3 IgG2a antibody inhibitor. Anti-Mouse TIM-3 Antibody (RMT3-23) blocks Tim-3 binding to phosphatidylserine (PtdSer) and carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1). Anti-Mouse TIM-3 Antibody (RMT3-23) inhibits phagocytosis of apoptotic cells in peritoneal exudate Mac1+ cells. Anti-Mouse TIM-3 Antibody (RMT3-23) can be used for the researches of inflammation and immunology, such as rheumatoid arthritis .
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Cat. No.: HY-P991068

Research Areas:  

Cancer

hT84.66-M5A is a humanized IgG1 antibody that targets carcinoembryonic antigen (CEA). The isotype control for hT84.66-M5A can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-N10631
CAS No.: 70858-45-6
Paucimannose is a mannosidic N-glycan epitope. It acts as a carcinoembryonic antigen, and a marker for cancer, stem cell properties and inflammation. Paucimannose mainly exists in plants and invertebrates. It consists of oligomannose-type N-glycans that preferentially bind to mannose-binding lectin. Paucimannose localizes on the surface of resting cells and translocates upon cell activation. It can be used in studies related to Pseudomonas aeruginosa infection, cancer and pancreatitis .
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Cat. No.: HY-P991198

Target:  

Tim3

Research Areas:  

Cancer

M6903 is a humanized monoclonal IgG2 antibody targeting T cell immunoglobulin and mucin domain-3 (TIM-3) (KD for human TIM-3 is 2.3 nM). M6903 binds to TIM-3, blocking the binding of TIM-3 to phosphatidylserine (PtdSer), carcinoembryonic antigen cell adhesion-related molecule 1 (CEACAM1), and galectin 9 (Gal-9), thus relieving TIM-3-mediated T cell inhibition and exerting the activities of activating antigen-specific T cells and enhancing anti-tumor immunity. M6903 is promising for research of cancers .
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Cat. No.: HY-121278
CAS No.: 39544-74-6
Synonyms: Benzotriptum
Research Areas:  

Inflammation/Immunology Cancer

Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines .
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Cat. No.: HY-P990852

Research Areas:  

Cancer

Anti-CEACAM7 Antibody (P3-7B) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM7. Anti-CEACAM7 Antibody (P3-7B) reacts with human carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7). Anti-CEACAM7 Antibody (P3-7B) can be used for detecting CEACAM7 in cancer.
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Cat. No.: HY-P9937
CAS No.: 154361-48-5
Synonyms: IMMU-4

Research Areas:  

Cancer

Arcitumomab is a murine anti-carcinoembryonic antigen (CEA) monoclonal antibody Fab’ fragment. Arcitumomab can be labeled with technetium-99m and can be used for single-photon emission computed tomography (SPECT) imaging .
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Cat. No.: HY-P990853

Research Areas:  

Cancer

Anti-CEACAM5 Antibody (4H11-8) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM5. Anti-CEACAM5 Antibody (4H11-8) reacts with human CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5). Anti-CEACAM5 Antibody (4H11-8) can be used for detecting CEACAM5 in cancer.
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Cat. No.: HY-P990854

Research Areas:  

Cancer

Anti-CEACAM1/3/5/6/8 Antibody (6G5j) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM1/3/5/6/8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) reacts with an antigen epitope shared by human carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 1, 3, 5, 6, and 8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) can be used for the detections of western blot, ELISA, immunofluorescence immunohistochemistry and flow cytometry in cancer .
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Cat. No.: HY-P705137
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM5; Cell Adhesion Molecule CEACAM5; Prev. CEA; Meconium antigen 100; Carcinoembryonic antigen-Related Cell Adhesion Molecule 5; Carcinoembryonic antigen-Related Cell Adhesion Molecule 5 Isoform 5D; CD66e; Carcinoembryonic antigen-Related Cell Adhesion Molecule 5 Isoform 3D; Carcinoembryonic antigen Related Cell Adhesion Molecule 5; CD66e antigen; CEA Cell Adhesion Molecule 5; Carcinoembryonic antigen
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P85091
Synonyms: CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD antigen CD66e

Host:  

Mouse

Application:  

WB, IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human

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