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Carnosol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (1) Endogenous Metabolite (2) Keap1-Nrf2 (2) Reference Standards (1) Ribosomal S6 Kinase (RSK) (2)
By Research Areas:	Cancer (3)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Carnosol* 15+ Cited Publications	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite	Cancer
Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

Carnosol (Standard)	Reference Standards Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite	Cancer
Carnosol (Standard) is the analytical standard of Carnosol. This product is intended for research and analytical applications. Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

Carnosol analog 1	Drug Derivative	Cancer
Carnosol analog 1 (Compound 10) is a derivative of carnosol. Carnosol analog 1 attenuates myotube atrophy (67.08% reversal) and adipocyte lipolysis in C26 tumor-conditioned models. Carnosol analog 1 alleviates cachexia-related weight loss without altering tumor progression in C26 tumor-bearing mice. Carnosol analog 1 can be used for the study of cancer cachexia .

7-O-Ethylepirosmanol Epirosmanol ethyl ether	Others	Others
7-O-Ethylepirosmanol (Epirosmanol ethyl ether) (Compound 6b) is the derivative of Epirosmanol (HY-111898). 7-O-Ethylepirosmanol is the degradation product of Carnosol (HY-N0643), the main antioxidant component in rosemary .

*Carnosol* 15+ Cited Publications	Classification of Application Fields Paramacrolobium coeruleum (Taub.) J.Léonard Food Preservation Research Plants Agricultural Research Terpenoids Labiatae Phenols Polyphenols Diterpenoids Disease Research Fields Source Classification Cancer	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite
Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

Carnosol (Standard)	Structural Classification Paramacrolobium coeruleum (Taub.) J.Léonard Terpenoids Labiatae Phenols Polyphenols Diterpenoids Plants Source Classification	Reference Standards Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite
Carnosol (Standard) is the analytical standard of Carnosol. This product is intended for research and analytical applications. Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

7-O-Ethylepirosmanol Epirosmanol ethyl ether	Structural Classification Paramacrolobium coeruleum (Taub.) J.Léonard Labiatae Phenols Polyphenols Plants Source Classification	Others
7-O-Ethylepirosmanol (Epirosmanol ethyl ether) (Compound 6b) is the derivative of Epirosmanol (HY-111898). 7-O-Ethylepirosmanol is the degradation product of Carnosol (HY-N0643), the main antioxidant component in rosemary .

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