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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Chronic myelogenous leukemia (CML)
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Chronic myelogenous leukemia (CML)" in MCE Product Catalog:
3
3 Cited Publications
GNF-5, the N-hydroxyethyl carboxamide analog of GNF-2, is an orally active Bcr-Abl inhibitor. GNF-5 has Bcr-Abl inhibition activity with an IC50 value of 0.22 µM. GNF-5 has good favorable pharmacokinetic properties. GNF-5 can be used for the research of kinds of cancer including chronic myelogenous leukemia (CML) and breast cancer .
1
1 Cited Publications
Synonyms: 18:0 Lyso-PC; LPC(18:0)
Category:
Target:
Cat. No.: HY-125771S
CAS No.: 327178-92-7
Synonyms: 18:0 Lyso-PC-d35; LPC(18:0)-d35
Cat. No.: HY-157389
AK-HW-90 (compound 2B) is a potent panBcr-Abl inhibitor with significant inhibitory activity against Imatinib (HY-15463)-resistant mutants. AK-HW-90 inhibits the resistance mutant Bcr-Abl T315I with an IC50 of 0.65 nM. AK-HW-90 has potential anticancer activity and can be used in the study of chronic myelogenous leukemia (CML) .
Cat. No.: HY-177273
CAS No.: 927697-17-4
Kinase modulator-1 (P142, MS: m/z445) is a kinase modulator. Kinase modulator-1 can inhibit Bcr-Abl activity, especially against drug-resistant mutant kinases (such as T315I Bcr-Abl). Kinase modulator-1 can be used for cancers like chronic myelogenous leukemia (CML) research .
Cat. No.: HY-P701877
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EXOSC5; Ribosomal RNA-Processing Protein 46; Exosome Component 5; Exosome Complex Component RRP46; RRP46; Exosome Component Rrp46; P12B; MGC12901; HRrp46p; Exosome Complex Exonuclease RRP46; Rrp46p; CABAC; RRP41B; CML28; Chronic myelogenous leukemia Tumor
Species:
Human
Source:
E. coli
Cat. No.: HY-P701878
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EXOSC5; Ribosomal RNA-Processing Protein 46; Exosome Component 5; Exosome Complex Component RRP46; RRP46; Exosome Component Rrp46; P12B; MGC12901; HRrp46p; Exosome Complex Exonuclease RRP46; Rrp46p; CABAC; RRP41B; CML28; Chronic myelogenous leukemia Tumor
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
