AK-HW-90
AK-HW-90 (compound 2B) is a potent panBcr-Abl inhibitor with significant inhibitory activity against Imatinib (HY-15463)-resistant mutants. AK-HW-90 inhibits the resistance mutant Bcr-AblT315I with an IC50 of 0.65 nM. AK-HW-90 has potential anticancer activity and can be used in the study of chronic myelogenous leukemia (CML).
For research use only. We do not sell to patients.
- Formula: C27H29N5O2S
- Molecular Weight:487.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
0.65 nM (Bcr-AblT315I)[1]
Chemical Information
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Molecular Weight 487.62
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Formula C27H29N5O2S
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SMILES
O=C(NC1=CC=C(C=C1)N2CCN(CC2)CC)NC(S3)=NC(C3=C4)=CC=C4C(C=CC=C5)=C5OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AK-HW-90 Related Classifications
HY-157389 Related Classifications
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