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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Complement+System
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Complement+System" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P9914
CAS No.: 219685-50-4
Synonyms: Anti-Human C5, Humanized Antibody; h5G1.1
Target:
Research Areas:
Cardiovascular Disease Infection Neurological Disease Inflammation/Immunology
3
3 Cited Publications
Cat. No.: HY-P1036
CAS No.: 206645-99-0
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P1036A
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-N9481
CAS No.: 56411-57-5
Synonyms: ARC1905
Target:
Research Areas:
Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system .
Cat. No.: HY-NP004
Synonyms: CVF
Cat. No.: HY-P991127
CAS No.: 2922766-89-8
Synonyms: DNTH103
Target:
Research Areas:
Cat. No.: HY-N0899
CAS No.: 11088-09-8
Cat. No.: HY-P99638
CAS No.: 2456407-94-4
Synonyms: ALXN-1720
Target:
Research Areas:
Cat. No.: HY-N2996
CAS No.: 107900-76-5
Category:
Infection Triterpenes Microorganisms Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields
Target:
Cat. No.: HY-160901
CAS No.: 1349637-14-4
Target:
Research Areas:
CP-289,503 is an inhibitor of the complement C5a receptor with an IC50 of 1 μM. C5a acts as an activator of leukocytes and phagocytes during complement system activation. The C5a receptor can bind to C5a, which can stimulate the upregulation of cell surface integrins and degranulation of inflammatory cells, leading to endothelial cell damage. C5a receptor inhibitors can block C5a signaling and inhibit a variety of inflammatory diseases .
Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Target:
Research Areas:
Cat. No.: HY-P1398
CAS No.: 301544-78-5
Target:
Research Areas:
Cat. No.: HY-W130878
CAS No.: 1806-26-4
Research Areas:
4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway .
Cat. No.: HY-P1398A
Target:
Research Areas:
Cat. No.: HY-174913
CAS No.: 1644670-23-4
Target:
Research Areas:
Factor B-IN-5 is an orally active complement factor B (CFB) inhibitor. Factor B-IN-5 alleviates kidney damage in diabetes nephropathy by inhibiting the over activation of complement system and improving mitochondrial function. Factor B-IN-5 can improve renal tubulointerstitial inflammation and fibrosis. Factor B-IN-5 can be used for research on diabetic nephropathy .
Cat. No.: HY-P5528
Cat. No.: HY-N19128
CAS No.: 1476801-10-1
Target:
Cat. No.: HY-N7955
CAS No.: 372096-70-3
Category:
Actaea heracleifolia (Kom.) J. Compton Tetracyclic Triterpenoids Terpenoids Ranunculaceae Plants
Target:
Cat. No.: HY-N17326
CAS No.: 242794-72-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
