1 Result for "

Ctx-L3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ctx-L3" in MCE Product Catalog:

製品番号: HY-181829
Target:  

EGFR PSMA LYTACs

研究分野:  

Cancer

Ctx-L3 is a selective EGFR PTAC (PSMA-targeted chimera) degrader (DC50: 4.3 pM in LNCaP cells) and LYTAC. Ctx-L3 recruits prostate-specific membrane antigen (PSMA) and mediates lysosomal degradation of EGFR in PSMA-positive prostate cancer cells. Ctx-L3 exhibits degrading activity against EGFR in prostate cancer cells. Ctx-L3 is applicable to related research on prostate cancer .
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