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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
Cyclic ADP-ribose
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "Cyclic ADP-ribose" in MCE Product Catalog:
2
7
7 Publications Verification
Synonyms: CZ-48
Target:
Research Areas:
Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production .
2
Cat. No.: HY-117804
CAS No.: 151898-26-9
Synonyms: 8-Bromo-Cyclic ADP-Ribose
Target:
Research Areas:
8-Br-cADPR (8-Bromo-Cyclic ADP-Ribose), a cyclic adenosine diphosphate (ADP)-ribose (cADPR) antagonist, is a TRPM2 ion channel antagonist. 8-Br-cADPR reduces renal damage and the expression of caspase-3 and TRPM2 .
Cat. No.: HY-175081
Synonyms: 8-Bromo-Cyclic ADP-Ribose sodium salt
Target:
Research Areas:
8-Br-cADPR (8-Bromo-Cyclic ADP-Ribose) sodium salt, a cyclic adenosine diphosphate (ADP)-ribose (cADPR) antagonist, is a TRPM2 ion channel antagonist. 8-Br-cADPR sodium salt reduces renal damage and the expression of caspase-3 and TRPM2 .
Cat. No.: HY-P990037
CAS No.: 2430792-01-9
Synonyms: GEN3014
Target:
Research Areas:
Cat. No.: HY-N7395B
Synonyms: cADPR diammonium
Research Areas:
Cyclic ADP-ribose diammonium (cADPR diammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD + by an ADP-ribosyl cyclase. Cyclic ADP-ribose diammonium increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels .
Cat. No.: HY-134269A
Synonyms: 7-deaza-8-bromo-cADPR disodium; 7-deaza-8-bromo-Cyclic ADP ribose disodium
Target:
Research Areas:
8-Br-7-CH-cADPR disodium (7-Deaza-8-bromo-cADPR) is a potent cADPR antagonist. 8-Br-7-CH-cADPR disodium shows partial inhibition of calcium elevation caused by sTIR dimerization. 8-Br-7-CH-cADPR disodium significantly decreases Paclitaxel (HY-B0015)-induced axon degeneration .
Cat. No.: HY-E71616
Target:
Research Areas:
2'-Phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC 2.4.99.20) catalyses both the removal of nicotinamide from NADP+, forming 2'-phospho-cyclic ADP-ribose, and the addition of nicotinate to the cyclic product, forming NAADP+, a calcium messenger that can mobilize intracellular Ca2+ stores and activate Ca2+ influx to regulate a wide range of physiological processes.
Cat. No.: HY-134269
CAS No.: 189876-06-0
Synonyms: 7-Deaza-8-bromo-cADPR; 7-Deaza-8-bromo-Cyclic ADP ribose
Target:
Research Areas:
8-Br-7-CH-cADPR (7-Deaza-8-bromo-cADPR) is a potent cADPR antagonist. 8-Br-7-CH-cADPR shows partial inhibition of calcium elevation caused by sTIR dimerization. 8-Br-7-CH-cADPR significantly decreases Paclitaxel (HY-B0015)-induced axon degeneration .
Cat. No.: HY-134305A
Synonyms: 8-Methylamino-NAD+ sodium
Target:
Research Areas:
8-MA-NAD+ (sodium) (8-Methylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-MA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations. 8-MA-NAD+ (sodium) can be used in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
Cat. No.: HY-134349A
Synonyms: 8-Piperidino-NAD+ sodium
Target:
Research Areas:
8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
Cat. No.: HY-P70731U
Purity: ≥ 95%, as determined by reducing SDS-PAGE.; ≥ 95% as determined by SEC-MALS.
Synonyms: CD38; NAD(+) Nucleosidase; CD38 Molecule; CD38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Differentiation 38; 2'-Phospho-ADP-Ribosyl Cyclase; CADPR Hydrolase 1; Cyclic ADP-Ribose Hydrolase 1; CD38 Antigen; CADPR1; ADPRC1; 2'-Phospho-ADP-Ribosyl Cyclase/2'-Phospho-Cyclic-ADP-Ribose Transferase; T10
Species:
Human
Source:
HEK293
Cat. No.: HY-P7791
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BST1; NAD(+) Nucleosidase; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; CADPR2; Cyclic ADP-Ribose Hydrolase; CD157; CADPr Hydrolase 2; BST-1; CADPR Hydrolase 2;
Species:
Human
Source:
HEK293
Cat. No.: HY-P7793
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BST1; NAD(+) Nucleosidase; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; CADPR2; Cyclic ADP-Ribose Hydrolase; CD157; CADPr Hydrolase 2; BST-1; CADPR Hydrolase 2;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76205
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BST1; NAD(+) Nucleosidase; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; CADPR2; Cyclic ADP-Ribose Hydrolase; CD157; CADPr Hydrolase 2; BST-1; CADPR Hydrolase 2;
Species:
Rat
Source:
HEK293
Cat. No.: HY-P7792
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BST1; NAD(+) Nucleosidase; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; CADPR2; Cyclic ADP-Ribose Hydrolase; CD157; CADPr Hydrolase 2; BST-1; CADPR Hydrolase 2;
Species:
Human
Source:
HEK293
Cat. No.: HY-P76204
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BST1; NAD(+) Nucleosidase; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; CADPR2; Cyclic ADP-Ribose Hydrolase; CD157; CADPr Hydrolase 2; BST-1; CADPR Hydrolase 2;
Species:
Rat
Source:
HEK293
Cat. No.: HY-P703809
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BST1; NAD(+) Nucleosidase; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; CADPR2; Cyclic ADP-Ribose Hydrolase; CD157; CADPr Hydrolase 2; BST-1; CADPR Hydrolase 2;
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P70022
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD38; NAD(+) Nucleosidase; CD38 Molecule; CD38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
