1 Result for "

Cys-LT7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cys-LT7" in MCE Product Catalog:

Cat. No.: HY-P11099
CAS No.: 1254540-73-2
Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease Cancer

Cys-LT7 is a transferrin receptor (TfR)-targeting peptide ligand. Cys-LT7 binds to a TfR site distinct from endogenous transferrin, mediates conjugated Doxorubicin (HY-15142A) delivery to TfR-overexpressed tumor cells, and exhibits low toxicity to TfR-low-expressed normal cells. Cys-LT7 is an L-configuration peptide susceptible to proteolytic enzymes, leading to poor biostability in peptide-drug conjugates. Cys-LT7 can be used for the research of glioblastoma, hepatocellular carcinoma, lung carcinoma .
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