1 Result for "

DETD35

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DETD35" in MCE Product Catalog:

製品番号: HY-164473
CAS 番号: 1836209-98-3
Target:  

ERK Akt STAT Apoptosis

研究分野:  

Cancer

DETD-35 is an inhibitor of the MEK-ERK, Akt, and STAT3 signaling pathways, which promotes cancer cell apoptosis (Apoptosis) and reduces cancer cell resistance to Vemurafenib (HY-12057). The IC50 values of DETD-35 against wild-type and mutant melanoma cell lines B16-F10, MeWo, SK-MEL-2, A2058c, and A375c are 2.7, 6.0, 3.9, 3.1, and 2.5 μM, respectively. DETD-35 holds promise for research in the field of anti-melanoma therapy .
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